Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SSQVCIPQTS CVLQKSKAVS QRPNLTVGRF NSAIPSTPSI RPNGTSGNKH NNNGFQQKTQ TLDSKLKKAV PQNHFLNKTA PKTQADVTTV NGTQTN
Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 57%.
The protein encoded by this gene is thought to be a mitotic spindle protein important to neural stem or progenitor cells. Mutations in this gene have been associated with spindle organization defects, including mitotic spindle defects, lagging chromosomes, and chromatin bridges. There is evidence that mutations in this gene are associated with Filippi syndrome, characterized by growth defects, microcephaly, intellectual disability, facial feature defects, and syndactyly. There is a pseudogene of this gene on chromosome 20. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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