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Invitrogen
COX3 Polyclonal Antibody
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Application
FIGURE: 1 / 4
COX3 Antibody (PA5-60120) in IHC (P)
Immunohistochemical analysis of COX3 in human skin using COX3 Polyclonal Antibody (Product # PA5-60120) shows moderate to strong granular cytoplasmic positivity in squamous epithelial cells.
Product Details
PA5-60120
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human COX3. Recombinant protein control fragment (Product #RP-98938).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YHSSLAPTPQ LGGHWPPTGI TPLNPL
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 85%.
Target Information
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Co3; Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3
Gene Aliases: COIII; COX3; COXIII; MT-CO3; MTCO3
UniProt ID: (Human) P00414
Entrez Gene ID: (Human) 4514
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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