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Product Details
PA5-63098
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HYPK. Recombinant protein control fragment (Product #RP-101704).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642600
Product Specific Information
Immunogen sequence: TAMSVIGDRR SREQKAKQER EKELAKVTIK KEDLELIMTE MEISRAAAER SLREHMGNVV EALIALT
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
Huntingtin-interacting protein K (HYPK) has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. It protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. HYPK is required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ20431; Huntingtin yeast partner K; Huntingtin-interacting protein K
Gene Aliases: C15orf63; HSPC136; HYPK
UniProt ID: (Human) Q9NX55
Entrez Gene ID: (Human) 25764
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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