Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: QGSLRKGRSS MRKNGSLQRP LQSGIPTLVV GSLRRSPTMV LRPQQFQFYQ PQGIPSSPSA VVVEMGSKPA LTGEPALTCI SRGSE
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 74%.
The SH3RF2 gene encodes a protein that has been shown to possess protein phosphatase 1 binding activity and ubiquitin protein ligase activity. This protein is involved in several cellular processes, including the positive regulation of the JNK cascade, protein autoubiquitination, and regulation of cellular protein metabolic processes. The protein is located in the nucleoplasm and mutations in the SH3RF2 gene have been associated with Ureter Transitional Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin-protein ligase SH3RF2; Heart protein phosphatase 1-binding protein; HEPP1; phosphatase 1 binding protein; POSH-eliminating RING protein; Protein phosphatase 1 regulatory subunit 39; protein phosphatase 1, regulatory subunit 39; RING finger protein 158; RING-type E3 ubiquitin transferase SH3RF2; SH3 domain-containing RING finger protein 2
Gene Aliases: HEPP1; POSH3; POSHER; PPP1R39; RNF158; SH3RF2
UniProt ID: (Human) Q8TEC5
Entrez Gene ID: (Human) 153769
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support