Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: RKETLSRRGPS ASSVAVMTSS TSDHHLDAAA ARQPNGVCRA GFERQHSLPS SEHLGADGGL YQIPLPSSQI PPQP
Highest antigen sequence identity to the following orthologs - mouse 72%, rat 69%.
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 54 kDa VacA-interacting protein; 54 kDa vimentin-interacting protein; 90 kDa SH3 protein interacting with Nck; AF3p21; dia interacting protein; Dia-interacting protein 1; diaphanous protein interacting protein; Diaphanous protein-interacting protein; DIP-1; MGC23891; NCK-interacting protein with SH3 domain; SH3 adapter protein SPIN90; SH3 protein interacting with Nck, 90 kDa; VIP54; WASP-interacting SH3-domain protein; WISH; Wiskott-Aldrich syndrome protein-interacting protein
Gene Aliases: AF3P21; DIP; DIP1; NCKIPSD; ORF1; SPIN90; VIP54; WASLBP; WISH
UniProt ID: (Human) Q9NZQ3
Entrez Gene ID: (Human) 51517
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