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Application
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CHIC1 Antibody (PA5-65699) in ICC/IF
Immunofluorescent staining of CHIC1 in human cell line U-2 OS shows localization to nuclear speckles, cytosol and vesicles. Samples were probed using a CHIC1 Polyclonal Antibody (Product # PA5-65699).
Product Details
PA5-65699
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CHIC1. Recombinant protein control fragment (Product #RP-106371).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663589
Product Specific Information
Immunogen sequence: EEEEAPPPPRV VSEEHLRRYA PDPVLVRGAG HITVFGL
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 95%.
Target Information
This gene encodes a cysteine-rich hydrophobic (CHIC) domain-containing protein, and is one of the few protein-coding genes found near the X-inactivation center. Studies in mouse indicate that the mouse ortholog of this gene is subject to X-inactivation in mouse. Experiments with other CHIC domain-containing family members show that the cysteine residues are palmitoylated post-translationally, resulting in membrane association. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain X-linked protein; cystein-rich hydrophobic domain 1; cysteine-rich hydrophobic domain 1 protein; Cysteine-rich hydrophobic domain-containing protein 1
Gene Aliases: BRX; CHIC1
UniProt ID: (Human) Q5VXU3
Entrez Gene ID: (Human) 53344
Performance Guarantee
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