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Product Details
PA5-65872
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CPOX. Recombinant protein control fragment (Product #RP-106543).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662825
Product Specific Information
Immunogen sequence: CDDYFFIAHRG ERRGIGGIFF DDLDSPSKEE VFRFVQSCAR AVVPSYIPLV KKHCDDSFTP QEKLWQQLRR GRYVEFNLLY DRGTKFGLFT PGSRIESILM SLPLTARWEY MHSPSENSKE AEILEVLRHP RDWV
Highest antigen sequence identity to the following orthologs - mouse 91%, rat 92%.
Target Information
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: coprogen oxidase; coproporphyrinogen-III oxidase, mitochondrial; coproporphyrinogenase; COX; Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Gene Aliases: CPO; CPOX; CPX; HCP
UniProt ID: (Human) P36551
Entrez Gene ID: (Human) 1371
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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