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Application
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CREST Antibody (PA5-66230) in ICC/IF
Immunofluorescent staining of CREST in human cell line RH-30 shows localization to nucleoplasm and cytosol. Samples were probed using a CREST Polyclonal Antibody (Product # PA5-66230).
Product Details
PA5-66230
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human CREST. Recombinant protein control fragment (Product #RP-106909).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662201
Product Specific Information
Immunogen sequence: MNLGPGALTQS GSSQGLHSQG SLSDAISTGL PPSSLLQGQI GNGPSHVSMQ
Highest antigen sequence identity to the following orthologs - mouse 86%, rat 86%.
Target Information
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium-responsive transactivator; SS18-like protein 1; synovial sarcoma translocation gene on chromosome 18-like 1; SYT homolog 1
Gene Aliases: CREST; KIAA0693; LP2261; SS18L1
UniProt ID: (Human) O75177
Entrez Gene ID: (Human) 26039
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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