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Immunogen sequence: EPTAERAHSVD PRDAWMLFVR QSDKGVNGKK RSRGKAKKLK FGLPGP
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 79%.
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake.
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