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Invitrogen
Laminin gamma-1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
Laminin gamma-1 Antibody (PA5-81991)
Relative expression in different tissues in IHC: Detection of differential expression levels of Laminin gamma-1 demonstrates antibody specificity. Immunohistochemical analysis of Laminin gamma-1 using anti-Laminin gamma-1 Polyclonal Antibody (Product #PA5-81991), shows significant staining of Laminin gamma-1 in placenta and shows minimal or weak staining in tonsil tissues. The relative expression levels of... View More
Product Details
PA5-81991
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LAMC1. Recombinant protein control fragment (Product #RP-101883).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789152
Product Specific Information
Immunogen sequence: ECREGFVGNR CDQCEENYFY NRSWPGCQEC PACYRLVKDK VADHRVKLQE LESLIANLGT GDEMVTDQAF EDRLKEAERE VMDLLREAQD VKDVDQNLMD RLQRVNNTLS SQISRLQNIR NTIEETGNLA EQARAHVENT ERLIEIASR
Target Information
Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing Type IV Collagen networks, Nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of alpha, beta and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin gamma-1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Laminin B2 chain; Laminin subunit gamma-1; laminin, gamma 1 (formerly LAMB2); Laminin-1 subunit gamma; Laminin-10 subunit gamma; Laminin-11 subunit gamma; Laminin-2 subunit gamma; Laminin-3 subunit gamma; Laminin-4 subunit gamma; Laminin-6 subunit gamma; Laminin-7 subunit gamma; Laminin-8 subunit gamma; Laminin-9 subunit gamma; S-LAM gamma; S-laminin subunit gamma
Gene Aliases: LAMB2; LAMC1
UniProt ID: (Human) P11047
Entrez Gene ID: (Human) 3915
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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