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Invitrogen
PRDX6 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
PRDX6 Antibody (PA5-82272)
Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of PRDX6 was observed specifically in PC-3 cells and in MCF-7 cells using anti-PRDX6 Polyclonal Antibody (Product #PA5-82272) in western blot. The relative expression levels of PRDX6 within each cell line is shown using RNA-Seq. {R... View More
Product Details
PA5-82272
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PRDX6. Recombinant protein control fragment (Product #RP-89190).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789432
Product Specific Information
Immunogen sequence: GGLLLGDVAP NFEANTTVGR IRFHDFLGDS WGILFSHPRD FTPVCTTELG RAAKLAPEFA KRNVKLIALS IDSVEDHLAW SKDINAYNCE EPTEKLPFPI IDDRNRELAI LLGMLDPAEK DEKGMPVTAR VVFVFGPDKK LKLSILYPA
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2; Antioxidant protein 2; epididymis secretory sperm binding protein Li 128m; Glutathione-dependent peroxiredoxin; Liver 2D page spot 40; LPC acyltransferase 5; Lysophosphatidylcholine acyltransferase 5; MGC46173; MSP23; NKEFA; Non-selenium glutathione peroxidase; NSGPx; PAGA; PAGB; Peroxiredoxin-6; Prx6; Red blood cells page spot 12
Gene Aliases: 1-Cys; aiPLA2; AOP2; HEL-S-128m; KIAA0106; NSGPx; p29; PRDX6; PRX
UniProt ID: (Human) P30041
Entrez Gene ID: (Human) 9588
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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