Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: ELSLAAAQNG FVDSAAAHMG AFKLNPG
ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Zic family member 2 (odd-paired homolog, Drosophila); Zinc finger protein of the cerebellum 2; Zinc finger protein ZIC 2
Gene Aliases: HPE5; ZIC2
UniProt ID: (Human) O95409
Entrez Gene ID: (Human) 7546
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