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Invitrogen
EWSR1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
EWSR1 Antibody (PA5-84576)
Relative expression in different tissues in IHC: Detection of differential expression levels of EWSR1 demonstrates antibody specificity. Immunohistochemical analysis of EWSR1 using anti-EWSR1 Polyclonal Antibody (Product #PA5-84576), shows significant staining of EWSR1 in testis and shows minimal or weak staining in skeletal muscle tissues. The relative expression levels of EWSR1 within each tissue is show... View More
Product Details
PA5-84576
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EWSR1. Recombinant protein control fragment (Product #RP-103916).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791727
Product Specific Information
Immunogen sequence: GDATVSYEDP PTAKAAVEWF DGKDFQGSKL KVSLARKKPP MNSMRGGLPP REGRGMPPPL RGGPG
Target Information
This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a ttranslocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AC002059.7; Ewing sarcoma breakpoint region 1; Ewing sarcoma breakpoint region 1 protein; Ewings sarcoma EWS-Fli1 (type 1) oncogene; EWS oncogene; EWS RNA-binding protein 1; EWS RNA-binding protein variant 6; RNA-binding protein EWS
Gene Aliases: bK984G1.4; EWS; EWS-FLI1; EWSR1
UniProt ID: (Human) Q01844
Entrez Gene ID: (Human) 2130
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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