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Invitrogen

CDA Polyclonal Antibody

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1 Published Figure

1 Reference

View all (16) CDA antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Application

CDA Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 5

CDA Antibody (PA5-84630) in ICC/IF

Immunofluorecent analysis of CDA in human cell line U-2 OS using CDA Polyclonal Antibody (Product # PA5-84630). Staining shows localization to nucleoplasm.

CDA Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

CDA Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of CDA demonstrates antibody specificity. Immunohistochemical analysis of CDA using anti-CDA Polyclonal Antibody (Product #PA5-84630), shows significant staining of CDA in bone marrow and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of CDA within each tissue is shown using RNA-Seq. {RE}

Product Details

PA5-84630

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CDA. Recombinant protein control fragment (Product #RP-103551).

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2791781

Product Specific Information

Immunogen sequence: GICAERTAIQ KAVSEGYKDF RAIAIASDMQ DDFISPCGAC RQVMREFGTN WPVYMTKPDG TYIVMTVQE

Target Information

This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Decitabine-induced DNA methylation-mediated transcriptomic reprogramming in human breast cancer cell lines; the impact of DCK overexpression.

Frontiers in pharmacology

Buocikova V,Tyciakova S,Pilalis E,Mastrokalou C,Urbanova M,Matuskova M,Demkova L,Medova V,Longhin EM,Rundén-Pran E,Dusinska M,Rios-Mondragon I,Cimpan MR,Gabelova A,Soltysova A,Smolkova B,Chatziioannou A

Published figure using CDA polyclonal antibody (Product # PA5-84630) in Western Blot

Tue Oct 25 00:00:00 UTC 2022

Decitabine-induced DNA methylation-mediated transcriptomic reprogramming in human breast cancer cell lines; the impact of DCK overexpression.

Frontiers in pharmacology

Published figure using CDA polyclonal antibody (Product # PA5-84630) in Western Blot

Tue Oct 25 00:00:00 UTC 2022

Bioinformatics

Protein Aliases: Cytidine aminohydrolase; Cytidine deaminase; cytosine nucleoside deaminase; EC 3.5.4.5; small cytidine deaminase

Gene Aliases: CDA; CDD

UniProt ID: (Human) P32320

Entrez Gene ID: (Human) 978

Function(s)

nucleoside binding cytidine deaminase activity protein binding zinc ion binding protein homodimerization activity deaminase

Process(es)

cell surface receptor signaling pathway pyrimidine-containing compound salvage cytidine deamination cytosine metabolic process negative regulation of cell growth pyrimidine nucleoside salvage negative regulation of nucleotide metabolic process protein homotetramerization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CDA Polyclonal Antibody

CDA Antibody (PA5-84630) in ICC/IF

Product Details

PA5-84630

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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CDA Polyclonal Antibody

CDA Antibody (PA5-84630) in ICC/IF

Product Details

PA5-84630

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID .st0{fill-rule:evenodd;clip-rule:evenodd;fill:#A2A2A2;}

Product Specific Information

Target Information

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