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Product Details
PA5-68802
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
synthetic peptide corresponding to a region of mouse ATF4 (aa 291-340).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2688575
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 79%; Human: 93%; Mouse: 100%; Rat: 100%; Sheep: 100%
Target Information
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Activating transcription factor 4; ATF 4; ATF4 protein; C/ATF; C/EBP-related ATF; cAMP-dependent transcription factor ATF-4; CREB 2; CREB-2; Cyclic AMP-dependent transcription factor ATF-4; Cyclic AMP-responsive element-binding protein 2; OTTHUMP00000199130; tax-re; tax-responsive enhancer element-binding protein 67 homolog; taxREB67 homolog
Gene Aliases: Atf-4; Atf4; C/ATF; CREB2; TAXREB67
UniProt ID: (Mouse) Q06507
Entrez Gene ID: (Mouse) 11911
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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