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Product Details
PR7013A
Product Specifications
Species
Human
Expression System
Insect cells
Amino acid sequence
879-1323
Tag
GST-tag
Molecular weight
77.2 kDa
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
See Label
Purification
purified
Storage buffer
50mM tris, pH 7.5, with 50% glycerol, 0.02% Triton X-100, 0.5mM EDTA, 2mM DTT, 150mM NaCl
Contains
no preservative
Storage conditions
-80° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Protein Form: Catalytic
Target Information
PASK is an evolutionarily conserved protein present in yeast, flies, and mammals. PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. It is a conserved gene product found in yeast as well as mammals. PASKIN contains two domains (PAS A and PAS B) as well as a serine/threonine kinase domain related to AMP kinases. PASKIN activity leads to decreased carbohydrate storage, as well as increased protein synthesis. PASKIN-dependent phosphorylation inhibits the activity of mammalian glycogen synthase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTMUSP00000024404; PAS domain-containing serine/threonine-protein kinase; PAS-kinase; per-arnt-sim (PAS) domain kinase
Gene Aliases: KIAA0135; PASK; PASKIN; STK37
UniProt ID: (Human) Q96RG2
Entrez Gene ID: (Human) 23178
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