A part of the JAK/STAT Pathway, STAT3 (Signal Transducer and Activator of Transcription 3) is phosphorylated at Tyr705 by the Janus family of tyrosine kinases.
For use in combination with the GFP-STAT3 physiological protein substrate (PV5212) and the LanthaScreen™ STAT3 GripTite™ cell line (K1488) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Conjugate
Tb (Terbium)/GFP (EmGFP)
Quantity
1 mg
Format
384-well Plate
Excitation/Emission
340⁄490, 520
Reactivity
Human
Shipping Condition
Dry Ice
Readout
End Point
Reactivity abrv
Hu
Target Enzyme
Tyrosine Kinases
Technique
TR-FRET
Validated Kinases
JAK1, JAK2, JAK3, TYK2
Contents & Storage
Terbium-labeled anti-STAT3 [pTyr705] antibody in HEPES buffered saline. Store at -20°C.