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Product Details
RP-101191
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
SYEKPISQKKIKIEPGIEPQRTDYYPEEMSPPLMNSVSPPQALLQENHPSVIVQPGKRPLPVESPDTQRKR
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111293. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Krueppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and the coregulators with which they interact. KLF6, also designated Zf9 or CPBP (core promoter-binding protein), and KLF3 are Kruppel-like zinc finger containing transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the collagen I promoter, suggesting KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Basic krueppel-like factor; basic kruppel like factor; basic Kruppel-like factor; CACCC-box-binding protein BKLF; Krueppel-like factor 3; Kruppel-like factor 3 (basic); MGC48279; TEF-2; transcript ch138
Gene Aliases: BKLF; KLF3
UniProt ID: (Human) P57682
Entrez Gene ID: (Human) 51274
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