Search Thermo Fisher Scientific
- Order Status
- Quick Order
-
Don't have an account ? Create Account
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (65%), Rat (65%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63704. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ZNF692, a zinc finger protein, is involved in several cellular processes including nucleolar organization and ribosome biogenesis. It interacts with nucleophosmin (NPM1), regulating nucleolar morphology by modifying NPM1's self-assembly properties and influencing protein synthesis. Knockdown of ZNF692 causes nucleolar redistribution of NPM1 and results in a decreased rate of protein synthesis. Additionally, ZNF692 plays a role in 40S ribosomal subunit maturation by forming a hub with the exosome complex and ribosome biogenesis factors. This gene is upregulated in certain cancers such as clear cell renal cell carcinoma (ccRCC), where its expression is associated with increased cell proliferation, migration, and poor overall survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AICAR responsive element binding protein; Zinc finger protein 692
Gene Aliases: AREBP; ZFP692; ZNF692
UniProt ID: (Human) Q9BU19
Entrez Gene ID: (Human) 55657
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support