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Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61410. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
SLX1 encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication. SLZ1A represents the more centromeric copy and SLZ1B represents the more telomeric copy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GIY-YIG domain-containing protein 1; SLX1 structure-specific endonuclease subunit homolog A; SLX1 structure-specific endonuclease subunit homolog B; SLX1A; SLX1B; Structure-specific endonuclease subunit SLX1
Gene Aliases: GIYD1; GIYD2; SLX1; SLX1A; SLX1B
UniProt ID: (Human) Q9BQ83
Entrez Gene ID: (Human) 548593, (Human) 79008
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