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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84710. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.
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Protein Aliases: enhancer of mRNA decapping 3 homolog; Enhancer of mRNA-decapping protein 3; hYjeF_N2; hYjeF_N2-15q23; LSM16 homolog; LSM16 homolog (EDC3, S. cerevisiae); yjeF domain containing; YjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; YjeF_N2
Gene Aliases: EDC3; LSM16; MRT50; PP844; YJDC; YJEFN2
UniProt ID: (Human) Q96F86
Entrez Gene ID: (Human) 80153
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