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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65951. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp434D229; Leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; MGC16925; p53-induced death domain-containing protein 1; p53-induced protein with a death domain
Gene Aliases: LRDD; PIDD; PIDD1
UniProt ID: (Human) Q9HB75
Entrez Gene ID: (Human) 55367
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