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Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84761. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described.
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Protein Aliases: 4-Feb; ADGRV1; Adhesion G-protein coupled receptor V1; G protein-coupled receptor 98; G-protein coupled receptor 98; monogenic; Monogenic audiogenic seizure susceptibility protein 1 homolog; monogenic, audiogenic seizure susceptibility 1 homolog; Usher syndrome type-2C protein; very large G protein-coupled receptor 1; Very large G-protein coupled receptor 1
Gene Aliases: ADGRV1; FEB4; GPR98; KIAA0686; KIAA1943; MASS1; USH2B; USH2C; VLGR1; VLGR1b
UniProt ID: (Human) Q8WXG9
Entrez Gene ID: (Human) 84059
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