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Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53730. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bicarbonate transporter related protein 1; CDPD; MGC126418; MGC126419; NaBC1; OTTHUMP00000030097; Sodium borate cotransporter 1; sodium-coupled borate cotransporter 1; Solute carrier family 4 member 11; solute carrier family 4, sodium bicarbonate transporter-like, member 11; solute carrier family 4, sodium borate transporter, member 11
Gene Aliases: BTR1; CDPD1; CHED; CHED2; dJ794I6.2; NABC1; SLC4A11
UniProt ID: (Human) Q8NBS3
Entrez Gene ID: (Human) 83959
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