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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54021. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HDAg-L-interacting protein NESI; hepatitis delta antigen-L interacting protein; liver regeneration p-53 related protein; LMBD1; LMBR1 domain-containing protein 1; Lysosomal cobalamin transport escort protein LMBD1; Nuclear export signal-interacting protein
Gene Aliases: BM-021; C6orf209; CD001; LMBD1; LMBRD1; MAHCF; MSTP044; NESI
UniProt ID: (Human) Q9NUN5
Entrez Gene ID: (Human) 55788
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