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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54058. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MuRF; MuRF-3; Muscle-specific RING finger protein; Muscle-specific RING finger protein 3; muscle-specific RING-finger protein 3; OTTHUMP00000122598; RING finger protein 30; tripartite motif-containing 54; Tripartite motif-containing protein 54
Gene Aliases: MURF; MURF-3; MURF3; RNF30; TRIM54
UniProt ID: (Human) Q9BYV2
Entrez Gene ID: (Human) 57159
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