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Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56217. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Clathrin coat assembly protein AP180 is a protein that in humans is encoded by the SNAP91 gene. Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 91 kDa synaptosomal-associated protein; assembly protein, 180kDa; Clathrin coat assembly protein AP180; Clathrin coat-associated protein AP180; Phosphoprotein F1-20; synaptosomal-associated protein, 91kDa homolog; synaptosome associated protein 91kDa
Gene Aliases: AP180; CALM; KIAA0656; SNAP91
UniProt ID: (Human) O60641
Entrez Gene ID: (Human) 9892
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