Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56248. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PHACTR1 plays a role in cell motility and in the formation of tubules by endothelial cells. PHACTR1 also binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Further, PHACTR1 regulates PPP1CA activity and is required for normal cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC126575; MGC126577; Phosphatase and actin regulator 1; RPEL repeat containing 1
Gene Aliases: dJ257A7.2; KIAA1733; PHACTR1; RPEL; RPEL1
UniProt ID: (Human) Q9C0D0
Entrez Gene ID: (Human) 221692
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