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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58381. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CARD-containing protein; caspase recruitment domain containing pro-apoptotic protein; Dermal papilla-derived protein 5; Deubiquitinating enzyme MINDY-3; family with sequence similarity 188, member A; Protein CARP; RP11-394I23.1; Ubiquitin carboxyl-terminal hydrolase MINDY-3
Gene Aliases: C10orf97; CARP; DERP5; FAM188A; MINDY3; MST126; MSTP126; My042
UniProt ID: (Human) Q9H8M7
Entrez Gene ID: (Human) 80013
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