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Highest antigen sequence indentity to the following orthologs: Mouse (63%), Rat (63%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83461. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the cytoskeletal BTB/kelch repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy.
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Protein Aliases: asterless; CC-CKR-8; CCR-8; centrosomal protein 152kDa; Centrosomal protein of 152 kDa; Cep152; CKRL1; CMKBR8; CY6; microcephaly, primary autosomal recessive 4
Gene Aliases: CEP152; KIAA0912; MCPH4; MCPH9; SCKL5
UniProt ID: (Human) O94986
Entrez Gene ID: (Human) 22995
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