Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (41%), Rat (41%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62148. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC39864; PML-RARA target gene encoding an Adaptor Molecule-1; PML-RARA-regulated adapter molecule 1; PRAM; PRAM-1 protein
Gene Aliases: PML-RAR; PRAM-1; PRAM1
UniProt ID: (Human) Q96QH2
Entrez Gene ID: (Human) 84106
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