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Highest antigen sequence indentity to the following orthologs: Mouse (43%), Rat (43%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62174. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ELSPBP1 (epididymal sperm-binding protein 1), also known as epididymal secretory protein 12 (E12), HE12 or EDDM12, is a 223 amino acid member of the seminal plasma protein family. ELSPBP1 is a secreted protein that is detected in cauda epididymal fluid and on sperm membrane. ELSPBP1 has phosphorylcholine-binding activity and has been shown to bind to spermatozoa upon ejaculation and is thought to play a role in sperm capacitation. N-glycosylated, ELSPBP1 contains four fibronectin type-II domains. The gene that encodes ELSPBP1 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymal protein 12; Epididymal secretory protein 12; Epididymal sperm-binding protein 1; epididymis luminal secretory protein 149; ESPB1; hE12
Gene Aliases: E12; EDDM12; EL149; ELSPBP1; HE12
UniProt ID: (Human) Q96BH3
Entrez Gene ID: (Human) 64100
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