Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62412. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dihydrofolate reductase 2, mitochondrial; dihydrofolate reductase like 1; dihydrofolate reductase pseudogene 4; Dihydrofolate reductase, mitochondrial; dihydrofolate reductase-like 1; Dihydrofolate reductase-like protein 1
Gene Aliases: DHFR2; DHFRL1; DHFRP4
UniProt ID: (Human) Q86XF0
Entrez Gene ID: (Human) 200895
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