Succinimidyl 3-(2-Pyridyldithio)Propionate (SPDP)
Succinimidyl 3-(2-Pyridyldithio)Propionate (SPDP)
Invitrogen™

Succinimidyl 3-(2-Pyridyldithio)Propionate (SPDP)

The heterobifunctional, crossslinker succinimidyl 3-(2-pyridyldithio)propionate (SPDP) enables one to covalently link two target groups. The succinimidyl ester chemically reacts withRead more
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Catalog NumberQuantity
S1531100 mg
Catalog number S1531
Price (USD)
427.00
Each
Add to cart
Quantity:
100 mg
Price (USD)
427.00
Each
Add to cart
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The heterobifunctional, crossslinker succinimidyl 3-(2-pyridyldithio)propionate (SPDP) enables one to covalently link two target groups. The succinimidyl ester chemically reacts with primary amines and after mild reduction of the dithiol, it can react form a disulfide with other thiols. Crosslinking reagents are useful for probing the spatial relationships and interactions within and between biomolecules.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Cell PermeabilityYes
DescriptionSPDP
FormSolid
Labeling MethodChemical Labeling
Molecular Weight (g/mol)312.36
PEGylatedNo
Quantity100 mg
Reactive MoietyNHS Ester, Pyridyldisulfide
SolubilityDMF, DMSO
Spacer Arm Length6.8 Å
Water SolubleNo
Chemical ReactivityAmine-Sulfhydryl
CleavableBy Thiols
Crosslinker TypeHeterobifunctional
FormatStandard
Product TypeCrosslinker
SpacerShort (<10 Å)
Unit SizeEach
Contents & Storage
Upon receipt store at -20°C protected from light.
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Frequently asked questions (FAQs)

Can you provide the shelf-life for Succinimidyl 3-(2-Pyridyldithio)Propionate (SPDP)?

Succinimidyl 3-(2-Pyridyldithio)Propionate (SPDP) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.

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