1-Bromobutane is used as an intermediate in organic synthesis and as a solvent for cleaning and degreasing. It acts as an alkylating agent as well as to prepare organometallic compounds such as n-butyllithium. It is also involved in the synthesis of procaine and tetracaine. It reacts with magnesium metal to prepare the Grignard reagent, which is used to form carbon-carbon bonds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Aplicaciones
El 1-bromobutano se utiliza como intermedio en la síntesis orgánica y como disolvente para la limpieza y el desengrasado. Actúa como un agente alquilante, así como para preparar compuestos organometálicos como el n-butillitio. También participa en la síntesis de la procaína y la tetracaína. Reacciona con el metal de magnesio para preparar el reactivo de Grignard, que se utiliza para formar enlaces de carbono-carbono.
Solubilidad
Miscible con etanol y éter dietílico. No miscible con agua.
Notas
Incompatible con agentes oxidantes fuertes, bases fuertes, magnesio, potasio, sodio y óxidos de sodio.
RUO – Research Use Only
General References:
- Chief Elk, J.; Benjamin, I. beta-Cyclodextrin at the water/1-bromobutane interface: molecular insight into reverse phase transfer catalysis. Langmuir 2015, 31 (18), 5086-5092.
- Paulechka, Y. U.; Kabo, G. J.; Blokhin, A. V.; Firaha, D. S. Thermodynamics of ionic liquid precursors. 1-Bromobutane and its isomers. J. Chem. Eng. Data 2011, 56 (12), 4891-4899.