Tris(hydroxymethyl)aminomethane is used as buffers in biochemistry and molecular biology laboratories. It is used as a primary standard to standardize acid solutions for chemical analysis. It finds application in cell membranes to increase its permeability. As an alternative to sodium bicarbonate, it used in the treatment of metabolic acidosis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Aplicaciones
El tris(hidroximetil)aminometano se utiliza como tampón en los laboratorios de bioquímica y de biología molecular. Se emplea como estándar primario para estandarizar las soluciones ácidas y realizar análisis químicos. Se usa en las membranas celulares para aumentar su permeabilidad. Como alternativa al bicarbonato de sodio, se utiliza en el tratamiento de la acidosis metabólica.
Solubilidad
Soluble en agua, etilenglicol, metanol, etanol, dimetilformamida, acetona, acetato de etilo, aceite de oliva, cloroformo y solución alcalina.
Notas
Higroscópico. Incompatible con bases y agentes oxidantes fuertes.
RUO – Research Use Only
Widely used biological buffer.
Filipiak, M. S.; Zloczewska, A.; Grzeskowiak, P.; Lynch, R.; Niedziolka, M. J. Tris (hydroxymethyl) aminomethane photooxidation on titania based photoanodes and its implication for photoelectrochemical biofuel cells. J. Power Sources 2015, 289, 17-21.
Lee, S. M.; Sim, K. S.; Lo, K. M. Synthesis, characterization and biological studies of diorganotin (IV) complexes with tris [(hydroxymethyl) aminomethane] Schiff bases. Inorg. Chim. Acta 2015, 429, 195-208.