Product References
Germline Neurofibromin 1 mutation enhances the anti-tumour immune response and decreases juvenile myelomonocytic leukaemia tumourigenicity.
British journal of haematology
Wang W,Li X,Qin X,Miao Y,Zhang Y,Li S,Yao R,Yang Y,Yu L,Zhu H,Song L,Mao S,Wang X,Chen J,Feng H,Li Y
100-20 was used in Cell Culture to demonstrate that germline NF1 mutations alone cannot directly drive JMML development and suggest a potential cell immunotherapy for JMML patients.
Sat Jul 01 00:00:00 UTC 2023
Exosomal miR-184 in the aqueous humor of patients with central serous chorioretinopathy: a potential diagnostic and prognostic biomarker.
Journal of nanobiotechnology
Yang JM,Kim SJ,Park S,Son W,Kim A,Lee J
100-20 was used in In vitro experiments to investigated exosomal microRNA in the aqueous humor of Central serous chorioretinopathy (CSC) patients using next-generation sequencing (NGS) to identify potential biomarkers associated with CSC pathogenesis.
Fri Jul 28 00:00:00 UTC 2023
Induced pluripotent stem cell model revealed impaired neurovascular interaction in genetic small vessel disease Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy.
Frontiers in cellular neuroscience
Zhang W,Zhao X,Qi X,Kimber SJ,Hooper NM,Wang T
100-20 was used in Cell Culture to establish induced pluripotent stem cell (iPSC) models from Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy patients and differentiated the iPSCs into the major neurovascular unit cell types including brain microvascular endothelial-like cells (BMECs), vascular mural cells (MCs), astrocytes and cortical projection neurons.
Wed Feb 14 00:00:00 UTC 2024
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.
Cell metabolism
Wieder N,Fried JC,Kim C,Sidhom EH,Brown MR,Marshall JL,Arevalo C,Dvela-Levitt M,Kost-Alimova M,Sieber J,Gabriel KR,Pacheco J,Clish C,Abbasi HS,Singh S,Rutter JC,Therrien M,Yoon H,Lai ZW,Baublis A,Subramanian R,Devkota R,Small J,Sreekanth V,Han M,Lim D,Carpenter AE,Flannick J,Finucane H,Haigis MC,Claussnitzer M,Sheu E,Stevens B,Wagner BK,Choudhary A,Shaw JL,Pablo JL,Greka A
100-20 was used in Cell Culture to find that c-MAF-inducing protein (CMIP) protects cells from FFA exposure by modulating Akt signaling.
Tue May 02 00:00:00 UTC 2023
Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages.
The Journal of cell biology
Pellegrino E,Aylan B,Bussi C,Fearns A,Bernard EM,Athanasiadi N,Santucci P,Botella L,Gutierrez MG
100-20 was used in In vitro experiments to find peroxisomes increased ROS levels during Mtb WT infection.
Mon Dec 04 00:00:00 UTC 2023
Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction.
Communications biology
Breitmeyer R,Vogel S,Heider J,Hartmann SM,Wüst R,Keller AL,Binner A,Fitzgerald JC,Fallgatter AJ,Volkmer H
100-20 was used in Cell Culture to present a co-culture model of neurons and microglia, both of human origin, to show increased susceptibility of neurons to microglia-like cells derived from SCZ patients.
Sat Apr 29 00:00:00 UTC 2023
SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways.
iScience
Jung HS,Suknuntha K,Kim YH,Liu P,Dettle ST,Sedzro DM,Smith PR,Thomson JA,Ong IM,Slukvin II
100-20 was used in Cell Culture to reveal that SOX18 forced expression at the mesodermal stage, in contrast to its homolog SOX17, has minimal effects on arterial specification of hemogenic endothelium, expression of HOXA genes and lymphoid differentiation.
Fri May 19 00:00:00 UTC 2023
Sphingosine-1-phosphate controls endothelial sphingolipid homeostasis via ORMDL.
EMBO reports
Sasset L,Chowdhury KH,Manzo OL,Rubinelli L,Konrad C,Maschek JA,Manfredi G,Holland WL,Di Lorenzo A
100-20 was used in Cell Culture to show that disrupting S1PR/ORMDL axis results in ceramide accrual, mitochondrial dysfunction, impaired signal transduction, all underlying endothelial dysfunction, early event in the onset of cardio- and cerebrovascular diseases.
Mon Jan 09 00:00:00 UTC 2023
Generation of multilineage liver organoids with luminal vasculature and bile ducts from human pluripotent stem cells via modulation of Notch signaling.
Stem cell research & therapy
Kim HJ,Kim G,Chi KY,Kim H,Jang YJ,Jo S,Lee J,Lee Y,Woo DH,Han C,Kim SK,Park HJ,Kim JH
100-20 was used in Cell Culture to demonstrate that mLOs can reproduce parenchymal and non-parenchymal cell interactions and suggest that their application can advance the precise modeling of liver diseases in vitro.
Fri Feb 03 00:00:00 UTC 2023
Analyzing mitochondrial respiration of human induced pluripotent stem cell-derived myeloid progenitors using Seahorse technology.
STAR protocols
Fan Y,Mizoguchi Y,Tatematsu M,Linder MI,Frenz S,Choi J,Klein C
100-20 was used in Cell Culture to describe a protocol to analyze and to quantify key parameters of mitochondrial respiration of iPSC-derived myeloid progenitors by the Seahorse XFe96 Analyzer.
Fri Mar 17 00:00:00 UTC 2023
ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages.
Nature microbiology
Aylan B,Bernard EM,Pellegrino E,Botella L,Fearns A,Athanasiadi N,Bussi C,Santucci P,Gutierrez MG
100-20 was used in Cell Culture to conclude that ATG7 and ATG14 are both required for restricting Mtb replication in human macrophages.
Mon May 01 00:00:00 UTC 2023
CXCL5 suppression recovers neovascularization and accelerates wound healing in diabetes mellitus.
Cardiovascular diabetology
Chen C,Lin LY,Chen JW,Chang TT
100-20 was used in Tissue/organ culture to explore the impacts and mechanistic insights of CXCL5 in neovasculogenesis and wound healing in diabetes mellitus.
Fri Jul 07 00:00:00 UTC 2023
Galectin-1 promotes angiogenesis and chondrogenesis during antler regeneration.
Cellular & molecular biology letters
Li X,Shi W,Wei G,Lv J,Wang D,Xing B,Zhou J,Zhao J,Sun H
100-20 was used in Cell Culture to find that Galectin-1 (GAL-1), which can be used as a marker in some tumors, is highly expressed in ASCs.
Mon May 15 00:00:00 UTC 2023
Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells.
Cell reports methods
Tamaoki N,Siebert S,Maeda T,Ha NH,Good ML,Huang Y,Vodnala SK,Haro-Mora JJ,Uchida N,Tisdale JF,Sweeney CL,Choi U,Brault J,Koontz S,Malech HL,Yamazaki Y,Isonaka R,Goldstein DS,Kimura M,Takebe T,Zou J,Stroncek DF,Robey PG,Kruhlak MJ,Restifo NP,Vizcardo R
100-20 was used in Cell Culture to demonstrate that organoid-induced HPCs can be differentiated into erythroid cells, macrophages, and T lymphocytes with current maturation protocols.
Mon Apr 24 00:00:00 UTC 2023
C-Myc-induced hypersialylation of small cell lung cancer facilitates pro-tumoral phenotypes of macrophages.
iScience
Tian L,Li H,Zhao P,Liu Y,Lu Y,Zhong R,Jin Y,Tan T,Cheng Y
100-20 was used in Cell Culture to provide a comprehensive overview of the cancer-specific immune signature of monocytes and macrophages and reveals tumor-associated biomarkers as potential therapeutic targets for SCLC.
Fri Oct 20 00:00:00 UTC 2023
The quality and quantity media-cultured mononuclear cell transplantation is safe and effective in ischemic hindlimb mouse model.
JVS-vascular science
Chinchalongporn W,Chruewkamlow N,Sermsathanasawadi N,Vorateera K,Jintaworn S,Wongwanit C,Ruangsetakit C
100-20 was used in Cell Culture to investigate in vitro proangiogenic and anti-inflammatory phenotypes and functions and the in vivo efficacy and safety of quality and quantity (QQ) media-cultured mononuclear cells (MNCs) compared with standard cultured MNCs from the peripheral blood of patients with chronic limb-threatening ischemia (CLTI) with atheosclerotic risk factors.
Tue Nov 14 00:00:00 UTC 2023
Directed Differentiation of Human iPSCs into Microglia-Like Cells Using Defined Transcription Factors.
Methods in molecular biology (Clifton, N.J.)
Chen SW,Wong YH
100-20 was used in Cell Culture to provide a stepwise protocol for the simple, robust, and efficient differentiation of hiPSCs into microglia-like cells (iMGs) by overexpression of SPI1 and CEBPA.
Mon Jun 12 00:00:00 UTC 2023
Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D mice.
JCI insight
Sleigh JN,Villarroel-Campos D,Surana S,Wickenden T,Tong Y,Simkin RL,Vargas JNS,Rhymes ER,Tosolini AP,West SJ,Zhang Q,Yang XL,Schiavo G
100-20 was used in In vivo experiments to suggest that selectively targeting muscles with BDNF-boosting therapies could represent a viable therapeutic strategy for CMT2D.
Mon May 08 00:00:00 UTC 2023
Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B.
The Journal of clinical investigation
Azad P,Zhou D,Tu HC,Villafuerte FC,Traver D,Rana TM,Haddad GG
100-20 was used in Cell Culture to conclude that HIKER regulates erythropoiesis in Monge's disease and acts through at least one specific target, CSNK2B, a casein kinase.
Thu Jun 01 00:00:00 UTC 2023
VEGF Induces Expression of Genes That Either Promote or Limit Relaxation of the Retinal Endothelial Barrier.
International journal of molecular sciences
McCann M,Li Y,Baccouche B,Kazlauskas A
100-20 was used in In vitro experiments to indicate that VEGF engages distinct sets of genes to induce and sustain barrier relaxation.
Wed Mar 29 00:00:00 UTC 2023
CD34dim cells identified as pluripotent stem cell-derived definitive hemogenic endothelium purified using bone morphogenetic protein 4.
Cell proliferation
Jeon SB,Han AR,Lee S,Lee SC,Lee MJ,Park SJ,Moon SH,Lee JY
100-20 was used in Cell Culture to develop a simple method to purify HE cells that were enriched in CD34dim cells.
Wed Feb 01 00:00:00 UTC 2023
Functional characterization of Alzheimer's disease genetic variants in microglia.
Nature genetics
Yang X,Wen J,Yang H,Jones IR,Zhu X,Liu W,Li B,Clelland CD,Luo W,Wong MY,Ren X,Cui X,Song M,Liu H,Chen C,Eng N,Ravichandran M,Sun Y,Lee D,Van Buren E,Jiang MZ,Chan CSY,Ye CJ,Perera RM,Gan L,Li Y,Shen Y
100-20 was used in In vitro experiments to show that AD variants exhibit allelic imbalance on target gene expression.
Sun Oct 01 00:00:00 UTC 2023
Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding.
Science advances
Riera-Domingo C,Leite-Gomes E,Charatsidou I,Zhao P,Carrá G,Cappellesso F,Mourao L,De Schepper M,Liu D,Serneels J,Alameh MG,Shuvaev VV,Geukens T,Isnaldi E,Prenen H,Weissman D,Muzykantov VR,Soenen S,Desmedt C,Scheele CLGJ,Sablina A,Di Matteo M,Martín-Pérez R,Mazzone M
100-20 was used in In vitro experiments to find that ECs at the PMN coexpress tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its cognate death receptor 5 (DR5).
Wed Mar 22 00:00:00 UTC 2023
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
Nature neuroscience
Dräger NM,Sattler SM,Huang CT,Teter OM,Leng K,Hashemi SH,Hong J,Aviles G,Clelland CD,Zhan L,Udeochu JC,Kodama L,Singleton AB,Nalls MA,Ichida J,Ward ME,Faghri F,Gan L,Kampmann M
100-20 was used in In vitro experiments to present a screening platform to systematically elucidate functional consequences of genetic perturbations in human induced pluripotent stem cell-derived microglia.
Thu Sep 01 00:00:00 UTC 2022
Notch1 promotes ordered revascularization through Semaphorin 3g modulation of downstream vascular patterning signalling factors.
The Journal of physiology
Hyun J,Lee M,Rehman J,Pajcini KV,Malik AB
100-20 was used in Sample Preparation (Western Blotting) to show that the Notch to Sema3g signalling axis functions as a feedback mechanism to sculpt the growing vasculature in multiple beds.
Tue Feb 01 00:00:00 UTC 2022
Quantitative Proteomics of Polarised Macrophages Derived from Induced Pluripotent Stem Cells.
Biomedicines
Murugesan G,Davidson L,Jannetti L,Crocker PR,Weigle B
100-20 was used in Cell Culture to generate and culture embroyoid bodies (iPSCs). Polarised to either M1 or M2, the macrophages were subjected to quantitative proteomic analysis gaining further insight into their functionalities.
Sun Jan 23 00:00:00 UTC 2022
Brevilin A Inhibits VEGF-Induced Angiogenesis through ROS-Dependent Mitochondrial Dysfunction.
Oxidative medicine and cellular longevity
Wei B,Hao Z,Zheng H,Qin Y,Zhao F,Shi L
100-20 was used in In vitro experiments to identify a new mechanism for antiangiogenic effect of BA in vascular EC, one that is based on the regulation of mitochondrial-dependent ROS overproduction.
Tue Jan 10 00:00:00 UTC 2023
Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy.
Cell reports
Chang Y,Syahirah R,Wang X,Jin G,Torregrosa-Allen S,Elzey BD,Hummel SN,Wang T,Li C,Lian X,Deng Q,Broxmeyer HE,Bao X
100-20 was used in Cell Culture to establish a robust platform for massive production of CAR neutrophils, paving the way to myeloid cell-based therapeutic strategies that would boost current cancer-treatment approaches.
Tue Jul 19 00:00:00 UTC 2022
Co-immunoprecipitation Assays.
Methods in molecular biology (Clifton, N.J.)
Evans IM,Paliashvili K
100-20 was used in Cell Culture to discuss the limitations of co-immunoprecipitation along with a step-by-step guide to performing and analysing co-immunoprecipitation experiments.
Tue Apr 26 00:00:00 UTC 2022
Engineered human blood-brain barrier microfluidic model for vascular permeability analyses.
Nature protocols
Hajal C,Offeddu GS,Shin Y,Zhang S,Morozova O,Hickman D,Knutson CG,Kamm RD
100-20 was used in Cell Culture to show that these properties, coupled with a functional brain endothelial expression profile and the capability to easily test several repeats with low reagent consumption, make this BBB model highly suitable for widespread use in academic and industrial laboratories.
Sat Jan 01 00:00:00 UTC 2022
Large-Scale Production of Wholly Cellular Bioinks via the Optimization of Human Induced Pluripotent Stem Cell Aggregate Culture in Automated Bioreactors.
Advanced healthcare materials
Ho DLL,Lee S,Du J,Weiss JD,Tam T,Sinha S,Klinger D,Devine S,Hamfeldt A,Leng HT,Herrmann JE,He M,Fradkin LG,Tan TK,Standish D,Tomasello P,Traul D,Dianat N,Ladi R,Vicard Q,Katikireddy K,Skylar-Scott MA
100-20 was used in In vitro experiments to demonstrate an optimized suspension culture-to-3D bioprinting pipeline that enables a sustainable approach to billion cell-scale organ engineering.
Thu Dec 01 00:00:00 UTC 2022
Generation of Cardiomyocytes and Endothelial Cells from Human iPSCs by Chemical Modulation of Wnt Signaling.
Methods in molecular biology (Clifton, N.J.)
Joachim A,Ye S,Zhao MT
100-20 was used in Cell Culture to provide protocols to generate iPSC-CMs and iPSC-ECs using small molecule-mediated monolayer differentiation.
Wed Jul 06 00:00:00 UTC 2022
Microvessels derived from hiPSCs are a novel source for angiogenesis and tissue regeneration.
Journal of tissue engineering
Gao X,Ma S,Xing X,Yang J,Xu X,Liang C,Yu Y,Liu L,Liao L,Tian W
100-20 was used in In vitro experiments to reveal that iMVs had remarkable similarities to natural blood vessels in structure and cellular composition, and were potent for vascular formation and self-organization.
Wed Jan 11 00:00:00 UTC 2023
Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis.
mBio
Santucci P,Aylan B,Botella L,Bernard EM,Bussi C,Pellegrino E,Athanasiadi N,Gutierrez MG
100-20 was used in Cell Culture to describe a dual live imaging approach to monitor mycobacterial pH homeostasis, host cell environment, and antibiotic action, and show that intracellular localization of M. tuberculosis affects the efficacy of pyrazinamide.
Tue Apr 26 00:00:00 UTC 2022
High-throughput 3D microvessel-on-a-chip model to study defective angiogenesis in systemic sclerosis.
Scientific reports
Kramer B,Corallo C,van den Heuvel A,Crawford J,Olivier T,Elstak E,Giordano N,Vulto P,Lanz HL,Janssen RAJ,Tessari MA
100-20 was used in Cell Culture to demonstrate that sera obtained from SSc patients can exert an anti-angiogenic effect on the 3D vessel model, opening the doors to screening for potential SSc drugs, enabling direct patient translatability and personalization of drug treatment.
Sat Oct 08 00:00:00 UTC 2022
Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease.
Cell stem cell
Jin M,Xu R,Wang L,Alam MM,Ma Z,Zhu S,Martini AC,Jadali A,Bernabucci M,Xie P,Kwan KY,Pang ZP,Head E,Liu Y,Hart RP,Jiang P
100-20 was used in Cell Culture to provide in vivo evidence that human microglia respond to pathological tau by exhibiting dystrophic phenotypes.
Thu Jul 07 00:00:00 UTC 2022
Development of a Vascularized Human Skin Equivalent with Hypodermis for Photoaging Studies.
Biomolecules
Sanchez MM,Tonmoy TI,Park BH,Morgan JT
100-20 was used in In vitro experiments to develop a novel method for generating HSE that include vascular and adipose components and demonstrated potential as an aging model using photoaging as an example.
Wed Dec 07 00:00:00 UTC 2022
Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons.
Cell reports
Huang CY,Nicholson MW,Wang JY,Ting CY,Tsai MH,Cheng YC,Liu CL,Chan DZH,Lee YC,Hsu CC,Hsu YH,Yang CF,Chang CMC,Ruan SC,Lin PJ,Lin JH,Chen LL,Hsieh ML,Cheng YY,Hsu WT,Lin YL,Chen CH,Hsu YH,Wu YT,Hacker TA,Wu JC,Kamp TJ,Hsieh PCH
100-20 was used in Cell Culture to study a a population-based human induced pluripotent stem cell (hiPSC) drug screening platform for toxicity assessment.
Tue Apr 05 00:00:00 UTC 2022
The relationship between epigenetic age and the hallmarks of aging in human cells.
Nature aging
Kabacik S,Lowe D,Fransen L,Leonard M,Ang SL,Whiteman C,Corsi S,Cohen H,Felton S,Bali R,Horvath S,Raj K
100-20 was used in In vitro experiments to show that although epigenetic aging is distinct from cellular senescence, telomere attrition and genomic instability, it is associated with nutrient sensing, mitochondrial activity and stem cell composition.
Wed Jun 01 00:00:00 UTC 2022
Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels.
BMC biology
O'Grady T,Njock MS,Lion M,Bruyr J,Mariavelle E,Galvan B,Boeckx A,Struman I,Dequiedt F
100-20 was used in Cell Culture to suggest a new paradigm in which the sorting and packaging of transcripts into EVs participate, together with transcription and RNA decay, in controlling RNA homeostasis and shape the cellular long RNA abundance profile.
Thu Mar 24 00:00:00 UTC 2022
3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration.
Cell stem cell
Manian KV,Galloway CA,Dalvi S,Emanuel AA,Mereness JA,Black W,Winschel L,Soto C,Li Y,Song Y,DeMaria W,Kumar A,Slukvin I,Schwartz MP,Murphy WL,Anand-Apte B,Chung M,Benoit DSW,Singh R
100-20 was used in Cell Culture to represent that the human 3D model described here provides a platform for investigating RPE-CC biology, AMD/MD pathophysiology, and testing new therapeutic interventions.
Thu May 06 00:00:00 UTC 2021
Fli1+ cells transcriptional analysis reveals an Lmo2-Prdm16 axis in angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Matrone G,Xia B,Chen K,Denvir MA,Baker AH,Cooke JP
Tue Aug 03 00:00:00 UTC 2021
Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.
Proceedings of the National Academy of Sciences of the United States of America
Lu TM,Houghton S,Magdeldin T,Durán JGB,Minotti AP,Snead A,Sproul A,Nguyen DT,Xiang J,Fine HA,Rosenwaks Z,Studer L,Rafii S,Agalliu D,Redmond D,Lis R
Tue Feb 23 00:00:00 UTC 2021
Mechanisms of angiogenic incompetence in Hutchinson-Gilford progeria via downregulation of endothelial NOS.
Aging cell
Gete YG,Koblan LW,Mao X,Trappio M,Mahadik B,Fisher JP,Liu DR,Cao K
Thu Jul 01 00:00:00 UTC 2021
Mechanisms of angiogenic incompetence in Hutchinson-Gilford progeria via downregulation of endothelial NOS.
Aging cell
Gete YG,Koblan LW,Mao X,Trappio M,Mahadik B,Fisher JP,Liu DR,Cao K
Thu Jul 01 00:00:00 UTC 2021
Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis.
EMBO reports
Nitzsche A,Pietilä R,Love DT,Testini C,Ninchoji T,Smith RO,Ekvärn E,Larsson J,Roche FP,Egaña I,Jauhiainen S,Berger P,Claesson-Welsh L,Hellström M
Wed Feb 03 00:00:00 UTC 2021
A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells.
EMBO reports
Li Y,Wang D,Wang H,Huang X,Wen Y,Wang B,Xu C,Gao J,Liu J,Tong J,Wang M,Su P,Ren S,Ma F,Li HD,Bresnick EH,Zhou J,Shi L
Thu Jan 07 00:00:00 UTC 2021
FOXK2 transcriptionally activating VEGFA induces apatinib resistance in anaplastic thyroid cancer through VEGFA/VEGFR1 pathway.
Oncogene
Feng H,Jin Z,Liang J,Zhao Q,Zhan L,Yang Z,Yan J,Kuang J,Cheng X,Qiu W
Fri Oct 01 00:00:00 UTC 2021
Activated mesangial cells induce glomerular endothelial cells proliferation in rat anti-Thy-1 nephritis through VEGFA/VEGFR2 and Angpt2/Tie2 pathway.
Cell proliferation
Zhao Y,Fu B,Chen P,Li Q,Ouyang Q,Zhang C,Cai G,Wu L,Chen X
Tue Jun 01 00:00:00 UTC 2021
Ex vivo conditioning of peripheral blood mononuclear cells of diabetic patients promotes vasculogenic wound healing.
Stem cells translational medicine
Tanaka R,Ito-Hirano R,Fujimura S,Arita K,Hagiwara H,Mita T,Itoh M,Kawaji H,Ogawa T,Watada H,Masuda H,Asahara T,Mizuno H
Tue Jun 01 00:00:00 UTC 2021
Combination of tumor necrosis factor-α and epidermal growth factor induces the adrenergic-to-mesenchymal transdifferentiation in SH-SY5Y neuroblastoma cells.
Cancer science
Huang Y,Tsubota S,Nishio N,Takahashi Y,Kadomatsu K
100-20 was used in Cell Culture to propose a mechanism of neuroblastoma transdifferentiation induced by extracellular growth factors, which can be controlled in clinical situations, providing a new therapeutic possibility.
Mon Feb 01 00:00:00 UTC 2021
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis.
Stem cells (Dayton, Ohio)
Pouyanfard S,Meshgin N,Cruz LS,Diggle K,Hashemi H,Pham TV,Fierro M,Tamayo P,Fanjul A,Kisseleva T,Kaufman DS
Wed Dec 01 00:00:00 UTC 2021
CRISPR editing of the GLI1 first intron abrogates GLI1 expression and differentially alters lineage commitment.
Stem cells (Dayton, Ohio)
Galat Y,Gu H,Perepitchka M,Taylor R,Yoon JW,Glukhova XA,Li XN,Beletsky IP,Walterhouse DO,Galat V,Iannaccone PM
Sat May 01 00:00:00 UTC 2021
CRISPR editing of the GLI1 first intron abrogates GLI1 expression and differentially alters lineage commitment.
Stem cells (Dayton, Ohio)
Galat Y,Gu H,Perepitchka M,Taylor R,Yoon JW,Glukhova XA,Li XN,Beletsky IP,Walterhouse DO,Galat V,Iannaccone PM
Sat May 01 00:00:00 UTC 2021
Mechanical loading stimulates bone angiogenesis through enhancing type H vessel formation and downregulating exosomal miR-214-3p from bone marrow-derived mesenchymal stem cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang X,Li X,Li J,Zhai L,Liu D,Abdurahman A,Zhang Y,Yokota H,Zhang P
Fri Jan 01 00:00:00 UTC 2021
Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells.
Journal of cell science
Holzner S,Bromberger S,Wenzina J,Neumüller K,Holper TM,Petzelbauer P,Bauer W,Weber B,Schossleitner K
100-20 was used in In vitro experiments to demonstrate that cingulin can counteract vascular leak at TJs, suggesting the existence of a novel mechanism in blood endothelial cells that protects barrier function during disease.
Wed Sep 01 00:00:00 UTC 2021
HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells.
Stem cells international
Kwon YW,Ahn HS,Lee JW,Yang HM,Cho HJ,Kim SJ,Lee SH,Yang HM,Jang HD,Kim SJ,Kim HS
Tue Jun 08 00:00:00 UTC 2021
Fine particulate matter (PM2.5) inhalation-induced alterations in the plasma lipidome as promoters of vascular inflammation and insulin resistance.
American journal of physiology. Heart and circulatory physiology
Hill BG,Rood B,Ribble A,Haberzettl P
Sat May 01 00:00:00 UTC 2021
Enhanced endothelial barrier function by monoclonal antibody activation of vascular endothelial cadherin.
American journal of physiology. Heart and circulatory physiology
Park KS,Schecterson L,Gumbiner BM
Thu Apr 01 00:00:00 UTC 2021
An in vivo model allowing continuous observation of human vascular formation in the same animal over time.
Scientific reports
Tsukada Y,Muramatsu F,Hayashi Y,Inagaki C,Su H,Iba T,Kidoya H,Takakura N
Tue Jan 12 00:00:00 UTC 2021
Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro.
Nature communications
Tan JJ,Guyette JP,Miki K,Xiao L,Kaur G,Wu T,Zhu L,Hansen KJ,Ling KH,Milan DJ,Ott HC
Tue Aug 17 00:00:00 UTC 2021
Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion.
iScience
Zhang Y,Guo A,Lyu C,Bi R,Wu Z,Li W,Zhao P,Niu Y,Na J,Xi JJ,Du Y
Fri Nov 19 00:00:00 UTC 2021
BMP-2 and VEGF-A modRNAs in collagen scaffold synergistically drive bone repair through osteogenic and angiogenic pathways.
Communications biology
Geng Y,Duan H,Xu L,Witman N,Yan B,Yu Z,Wang H,Tan Y,Lin L,Li D,Bai S,Fritsche-Danielson R,Yuan J,Chien K,Wei M,Fu W
Tue Jan 19 00:00:00 UTC 2021
Stem-cell-derived human microglia transplanted into mouse brain to study human disease.
Nature protocols
Fattorelli N,Martinez-Muriana A,Wolfs L,Geric I,De Strooper B,Mancuso R
100-20 was used in Sample Preparation to explain the step-by-step workflow that includes in vitro microglia differentiation from human PSCs, transplantation into the mouse brain and quantitative analysis of engraftment. This approach is more optimized and more efficient approach that yields up to 80% chimerism when compared to current differentiation and xenotransplantation protocols.
Mon Feb 01 00:00:00 UTC 2021
Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases.
Science advances
Trapecar M,Wogram E,Svoboda D,Communal C,Omer A,Lungjangwa T,Sphabmixay P,Velazquez J,Schneider K,Wright CW,Mildrum S,Hendricks A,Levine S,Muffat J,Lee MJ,Lauffenburger DA,Trumper D,Jaenisch R,Griffith LG
100-20 was used in In vitro experiments to develop a mesofluidic platform technology to study gut-liver-cerebral interactions in the context of Parkinson's disease (PD).
Fri Jan 01 00:00:00 UTC 2021
Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin α5.
Cell reports
Richards M,Pal S,Sjöberg E,Martinsson P,Venkatraman L,Claesson-Welsh L
Tue Jun 22 00:00:00 UTC 2021
Mitophagy mediates metabolic reprogramming of induced pluripotent stem cells undergoing endothelial differentiation.
The Journal of biological chemistry
Krantz S,Kim YM,Srivastava S,Leasure JW,Toth PT,Marsboom G,Rehman J
Wed Dec 01 00:00:00 UTC 2021
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells.
Cell death & disease
Meng Y,Song C,Ren Z,Li X,Yang X,Ai N,Yang Y,Wang D,Zhan M,Wang J,Lei CL,Liu W,Ge W,Lu L,Chen G
Mon Nov 29 00:00:00 UTC 2021
Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy.
Nature communications
Bent EH,Millán-Barea LR,Zhuang I,Goulet DR,Fröse J,Hemann MT
Thu Oct 28 00:00:00 UTC 2021
Patient-specific iPSC-derived endothelial cells reveal aberrant p38 MAPK signaling in atypical hemolytic uremic syndrome.
Stem cell reports
Zhou D,Tan Y,Liu X,Tang L,Wang H,Shen J,Wang W,Zhuang L,Tao J,Su J,Gong T,Liu X,Liang P,Yu F,Zhao M
Tue Sep 14 00:00:00 UTC 2021
Personalized medicine for reconstruction of critical-size bone defects - a translational approach with customizable vascularized bone tissue.
NPJ Regenerative medicine
Kengelbach-Weigand A,Thielen C,Bäuerle T,Götzl R,Gerber T,Körner C,Beier JP,Horch RE,Boos AM
Thu Aug 19 00:00:00 UTC 2021
Gamma irradiation exposure for collapsed cell junctions and reduced angiogenesis of 3-D in vitro blood vessels.
Scientific reports
Na K,Cho Y,Choi DH,Park MJ,Yang JH,Chung S
Tue Sep 14 00:00:00 UTC 2021
SOX17 integrates HOXA and arterial programs in hemogenic endothelium to drive definitive lympho-myeloid hematopoiesis.
Cell reports
Jung HS,Uenishi G,Park MA,Liu P,Suknuntha K,Raymond M,Choi YJ,Thomson JA,Ong IM,Slukvin II
100-20 was used in In vitro experiments to investigate the role and mechanisms of SOX17 in human pluripotent stem cells.
Tue Feb 16 00:00:00 UTC 2021
Fabrication of centimeter-sized 3D constructs with patterned endothelial cells through assembly of cell-laden microbeads as a potential bone graft.
Acta biomaterialia
Yang G,Mahadik B,Choi JY,Yu JR,Mollot T,Jiang B,He X,Fisher JP
100-20 was used in Cell Culture to prepare collagen microbeads loaded with human bone marrow derived mesenchymal stem cells (BMSCs) using a microfluidic approach.
Mon Feb 01 00:00:00 UTC 2021
PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells.
Cell death & disease
De Smedt J,van Os EA,Talon I,Ghosh S,Toprakhisar B,Furtado Madeiro Da Costa R,Zaunz S,Vazquez MA,Boon R,Baatsen P,Smout A,Verhulst S,van Grunsven LA,Verfaillie CM
Thu Jan 14 00:00:00 UTC 2021
Novel culture media enhances mononuclear cells from patients with chronic limb-threatening ischemia to increase vasculogenesis and anti-inflammatory effect.
Stem cell research & therapy
Chruewkamlow N,Pruekprasert K,Phutthakunphithak P,Acharayothin O,Prapassaro T,Hongku K,Hahtapornsawan S,Puangpunngam N,Chinsakchai K,Wongwanit C,Ruangsetakit C,Sermsathanasawadi N
100-20 was used in Cell Culture to evaluate the use of Quality and Quantity culture media to culture mononuclear cells from chronic limb-threatening ischemia patients.
Tue Sep 28 00:00:00 UTC 2021
The CCL2-CCR2 astrocyte-cancer cell axis in tumor extravasation at the brain.
Science advances
Hajal C,Shin Y,Li L,Serrano JC,Jacks T,Kamm RD
100-20 was used in Tissue/organ culture to investigate if astrocytes promote cancer cell transmigration via their secretion of C-C motif chemokine ligand 2 (CCL2) using a a three-dimensional in vitro blood-brain barrier microvascular model.
Tue Jun 01 00:00:00 UTC 2021
Mitogen-Inducible Gene 6 Inhibits Angiogenesis by Binding to SHC1 and Suppressing Its Phosphorylation.
Frontiers in cell and developmental biology
Liu L,Xing L,Chen R,Zhang J,Huang Y,Huang L,Xie B,Ren X,Wang S,Kuang H,Lin X,Kumar A,Kim JK,Lee C,Li X
100-20 was used in In vitro experiments to show that MIG6 is a potent endogenous inhibitor of angiogenesis that may have therapeutic value in anti-angiogenic therapy.
Fri Mar 12 00:00:00 UTC 2021
Interstitial flow enhances the formation, connectivity, and function of 3D brain microvascular networks generated within a microfluidic device.
Lab on a chip
Winkelman MA,Kim DY,Kakarla S,Grath A,Silvia N,Dai G
100-20 was used in Cell Culture to highlight the importance of interstitial flow in the in vitro generation of perfused brain microvascular networks with characteristics similar to those of the human blood-brain barrier.
Tue Dec 21 00:00:00 UTC 2021
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis.
Nature
Nikolaev M,Mitrofanova O,Broguiere N,Geraldo S,Dutta D,Tabata Y,Elci B,Brandenberg N,Kolotuev I,Gjorevski N,Clevers H,Lutolf MP
Tue Sep 01 00:00:00 UTC 2020
Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.
Cell
Zhang L,Li Z,Skrzypczynska KM,Fang Q,Zhang W,O'Brien SA,He Y,Wang L,Zhang Q,Kim A,Gao R,Orf J,Wang T,Sawant D,Kang J,Bhatt D,Lu D,Li CM,Rapaport AS,Perez K,Ye Y,Wang S,Hu X,Ren X,Ouyang W,Shen Z,Egen JG,Zhang Z,Yu X
Thu Apr 16 00:00:00 UTC 2020
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.
Cell
Monteil V,Kwon H,Prado P,Hagelkrüys A,Wimmer RA,Stahl M,Leopoldi A,Garreta E,Hurtado Del Pozo C,Prosper F,Romero JP,Wirnsberger G,Zhang H,Slutsky AS,Conder R,Montserrat N,Mirazimi A,Penninger JM
100-20 was used in Cell Culture to show that SARS-CoV-2 can directly infect engineered human blood vessel organoids and human kidney organoids, which can be inhibited by hrsACE2.
Thu May 14 00:00:00 UTC 2020
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.
Cell
Monteil V,Kwon H,Prado P,Hagelkrüys A,Wimmer RA,Stahl M,Leopoldi A,Garreta E,Hurtado Del Pozo C,Prosper F,Romero JP,Wirnsberger G,Zhang H,Slutsky AS,Conder R,Montserrat N,Mirazimi A,Penninger JM
100-20 was used in Cell Culture to show that SARS-CoV-2 can directly infect engineered human blood vessel organoids and human kidney organoids, which can be inhibited by hrsACE2.
Thu May 14 00:00:00 UTC 2020
Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development.
Cell stem cell
Crosse EI,Gordon-Keylock S,Rybtsov S,Binagui-Casas A,Felchle H,Nnadi NC,Kirschner K,Chandra T,Tamagno S,Webb DJ,Rossi F,Anderson RA,Medvinsky A
100-20 was used in In vitro experiments to identify secreted signals underlying human HSC development, combining spatial transcriptomics analysis of dorsoventral polarized signaling in the aorta with gene expression profiling of sorted cell populations and single cells.
Thu Nov 05 00:00:00 UTC 2020
Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury.
The Journal of clinical investigation
Masoud AG,Lin J,Azad AK,Farhan MA,Fischer C,Zhu LF,Zhang H,Sis B,Kassiri Z,Moore RB,Kim D,Anderson CC,Vederas JC,Adam BA,Oudit GY,Murray AG
Thu Jan 02 00:00:00 UTC 2020
Methylation in pericytes after acute injury promotes chronic kidney disease.
The Journal of clinical investigation
Chou YH,Pan SY,Shao YH,Shih HM,Wei SY,Lai CF,Chiang WC,Schrimpf C,Yang KC,Lai LC,Chen YM,Chu TS,Lin SL
Tue Sep 01 00:00:00 UTC 2020
An allosteric peptide inhibitor of HIF-1α regulates hypoxia-induced retinal neovascularization.
Proceedings of the National Academy of Sciences of the United States of America
Usui-Ouchi A,Aguilar E,Murinello S,Prins M,Gantner ML,Wright PE,Berlow RB,Friedlander M
Tue Nov 10 00:00:00 UTC 2020
A novel method to improve the osteogenesis capacity of hUCMSCs with dual-directional pre-induction under screened co-culture conditions.
Cell proliferation
Rong Q,Li S,Zhou Y,Geng Y,Liu S,Wu W,Forouzanfar T,Wu G,Zhang Z,Zhou M
Sat Feb 01 00:00:00 UTC 2020
Biallelic correction of sickle cell disease-derived induced pluripotent stem cells (iPSCs) confirmed at the protein level through serum-free iPS-sac/erythroid differentiation.
Stem cells translational medicine
Haro-Mora JJ,Uchida N,Demirci S,Wang Q,Zou J,Tisdale JF
Fri May 01 00:00:00 UTC 2020
Biallelic correction of sickle cell disease-derived induced pluripotent stem cells (iPSCs) confirmed at the protein level through serum-free iPS-sac/erythroid differentiation.
Stem cells translational medicine
Haro-Mora JJ,Uchida N,Demirci S,Wang Q,Zou J,Tisdale JF
Fri May 01 00:00:00 UTC 2020
Adaptation within embryonic and neonatal heart environment reveals alternative fates for adult c-kit+ cardiac interstitial cells.
Stem cells translational medicine
Wang BJ,Alvarez R,Muliono A,Sengphanith S,Monsanto MM,Weeks J,Sacripanti R,Sussman MA
Fri May 01 00:00:00 UTC 2020
Adaptation within embryonic and neonatal heart environment reveals alternative fates for adult c-kit+ cardiac interstitial cells.
Stem cells translational medicine
Wang BJ,Alvarez R,Muliono A,Sengphanith S,Monsanto MM,Weeks J,Sacripanti R,Sussman MA
Fri May 01 00:00:00 UTC 2020
AKAP12 deficiency impairs VEGF-induced endothelial cell migration and sprouting.
Acta physiologica (Oxford, England)
Benz PM,Ding Y,Stingl H,Loot AE,Zink J,Wittig I,Popp R,Fleming I
Wed Jan 01 00:00:00 UTC 2020
AKAP12 deficiency impairs VEGF-induced endothelial cell migration and sprouting.
Acta physiologica (Oxford, England)
Benz PM,Ding Y,Stingl H,Loot AE,Zink J,Wittig I,Popp R,Fleming I
Wed Jan 01 00:00:00 UTC 2020
miR‑126 regulates the progression of epithelial ovarian cancer in vitro and in vivo by targeting VEGF‑A.
International journal of oncology
Liu L,Yuan L,Huang D,Han Q,Cai J,Wang S,Cao J
100-20 was used in Sample Preparation (Western Blotting) to investigate miRNA-126 in ovarian cancer.
Tue Sep 01 00:00:00 UTC 2020
Peroxidasin is essential for endothelial cell survival and growth signaling by sulfilimine crosslink-dependent matrix assembly.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lee SW,Kim HK,Naidansuren P,Ham KA,Choi HS,Ahn HY,Kim M,Kang DH,Kang SW,Joe YA
Sat Aug 01 00:00:00 UTC 2020
Advancing human induced pluripotent stem cell-derived blood-brain barrier models for studying immune cell interactions.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Nishihara H,Gastfriend BD,Soldati S,Perriot S,Mathias A,Sano Y,Shimizu F,Gosselet F,Kanda T,Palecek SP,Du Pasquier R,Shusta EV,Engelhardt B
Tue Dec 01 00:00:00 UTC 2020
cMet agonistic antibody attenuates apoptosis in ischaemia-reperfusion-induced kidney injury.
Journal of cellular and molecular medicine
An JN,Li L,Lee J,Yu SS,Lee J,Kim YC,Kim DK,Oh YK,Lim CS,Kim YS,Kim S,Yang SH,Lee JP
Fri May 01 00:00:00 UTC 2020
Role of Elevated SFLT-1 on the Regulation of Placental Transporters in Women With Pre-Eclampsia.
Clinical and translational science
Kojovic D,V Workewych N,Piquette-Miller M
Fri May 01 00:00:00 UTC 2020
Hybrid cardiovascular sourced extracellular matrix scaffolds as possible platforms for vascular tissue engineering.
Journal of biomedical materials research. Part B, Applied biomaterials
Reid JA,Callanan A
Wed Apr 01 00:00:00 UTC 2020
Rewiring of endogenous signaling pathways to genomic targets for therapeutic cell reprogramming.
Nature communications
Krawczyk K,Scheller L,Kim H,Fussenegger M
Thu Jan 30 00:00:00 UTC 2020
Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2.
Science advances
Zhao G,Weiner AI,Neupauer KM,de Mello Costa MF,Palashikar G,Adams-Tzivelekidis S,Mangalmurti NS,Vaughan AE
100-20 was used in In vitro experiments to demonstrate that lung endothelium possesses substantial regenerative capacity and lineage tracing reveals that native endothelium is the source of vascular repair after influenza injury.
Sun Nov 01 00:00:00 UTC 2020
Inducible Forward Programming of Human Pluripotent Stem Cells to Hemato-endothelial Progenitor Cells with Hematopoietic Progenitor Potential.
Stem cell reports
Lange L,Hoffmann D,Schwarzer A,Ha TC,Philipp F,Lenz D,Morgan M,Schambach A
Tue Jan 14 00:00:00 UTC 2020
iPSC-Based Modeling of RAG2 Severe Combined Immunodeficiency Reveals Multiple T Cell Developmental Arrests.
Stem cell reports
Themeli M,Chhatta A,Boersma H,Prins HJ,Cordes M,de Wilt E,Farahani AS,Vandekerckhove B,van der Burg M,Hoeben RC,Staal FJT,Mikkers HMM
Tue Feb 11 00:00:00 UTC 2020
iPSC-derived progenitor stromal cells provide new insights into aberrant musculoskeletal development and resistance to cancer in down syndrome.
Scientific reports
Galat Y,Perepitchka M,Elcheva I,Iannaccone S,Iannaccone PM,Galat V
Thu Aug 06 00:00:00 UTC 2020
Cdc42 subcellular relocation in response to VEGF/NRP1 engagement is associated with the poor prognosis of colorectal cancer.
Cell death & disease
Ma LL,Guo LL,Luo Y,Liu GL,Lei Y,Jing FY,Zhang YL,Tong GH,Jing ZL,Shen L,Tang MS,Ding YQ,Deng YJ
Thu Mar 05 00:00:00 UTC 2020
Modulating electrospun polycaprolactone scaffold morphology and composition to alter endothelial cell proliferation and angiogenic gene response.
PloS one
Reid JA,McDonald A,Callanan A
Tue Dec 08 00:00:00 UTC 2020
Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia.
STAR protocols
Ryan SK,Jordan-Sciutto KL,Anderson SA
Fri Dec 18 00:00:00 UTC 2020
The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting.
Cell reports
Tan JME,van der Stoel MM,van den Berg M,van Loon NM,Moeton M,Scholl E,van der Wel NN,Kovačević I,Hordijk PL,Loregger A,Huveneers S,Zelcer N
100-20 was used in Cell Culture to propose a mechanistic link between regulation of cholesterol homeostasis by the MARCH6-SQLE axis and endothelial integrity and angiogenesis.
Tue Aug 04 00:00:00 UTC 2020
Differentiation of Human Induced Pluripotent Stem Cells (hiPSCs) into Osteoclasts.
Bio-protocol
Chen IP
100-20 was used in Cell Culture to study efficient differentiation of hiPSCs into osteoclasts using a three-stage protocol which does not require a co-culture system; induces EBs into mesoderm differentiation in a homogenous manner; uses less cytokines for differentiation; requires only a short time for osteoclast maturation and produces sufficient numbers of osteoclasts for subsequent molecular analyses.
Sun Dec 20 00:00:00 UTC 2020
Increased vasculogenesis of endothelial cells in hyaluronic acid augmented fibrin-based natural hydrogels - from in vitro to in vivo models.
European cells & materials
Lin HC,Wang CK,Tung YC,Chiu FY,Su YP
100-20 was used in Cell Culture to study the unsatisfactory mechanical strength and degree of vascularisation of Fibrin-based hydrogels.
Sun Sep 20 00:00:00 UTC 2020
Targeting the ERβ/Angiopoietin-2/Tie-2 signaling-mediated angiogenesis with the FDA-approved anti-estrogen Faslodex to increase the Sunitinib sensitivity in RCC.
Cell death & disease
Gu J,Zhang Y,Han Z,Gao L,Cui J,Sun Y,Niu Y,You B,Huang CP,Chang C,Wang X,Yeh S
Thu May 14 00:00:00 UTC 2020
B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression.
Cell death & disease
Wang R,Ma Y,Zhan S,Zhang G,Cao L,Zhang X,Shi T,Chen W
Thu Jan 23 00:00:00 UTC 2020
Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification.
Cell reports
Qiu J,Nordling S,Vasavada HH,Butcher EC,Hirschi KK
100-20 was used in In vitro experiments to demonstarte the use of retinoic acid in promoting endothelial cell cycle early G1 state thus stimulating HSPCs specification towards hemogenic endothelial cells; insight for ex vivo regenrative medicine applications.
Tue Dec 01 00:00:00 UTC 2020
Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling.
eLife
Xiong Y,Scerbo MJ,Seelig A,Volta F,O'Brien N,Dicker A,Padula D,Lickert H,Gerdes JM,Berggren PO
100-20 was used in Cell Culture to investigate effects of cilia on islet vascularisation.
Tue Nov 17 00:00:00 UTC 2020
Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells.
Cell reports
Wesely J,Kotini AG,Izzo F,Luo H,Yuan H,Sun J,Georgomanoli M,Zviran A,Deslauriers AG,Dusaj N,Nimer SD,Leslie C,Landau DA,Kharas MG,Papapetrou EP
100-20 was used in Cell Culture to empower efforts to therapeutically target AML LSCs.
Tue Jun 02 00:00:00 UTC 2020
Adult Tissue Extracellular Matrix Determines Tissue Specification of Human iPSC-Derived Embryonic Stage Mesodermal Precursor Cells.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Ullah I,Busch JF,Rabien A,Ergün B,Stamm C,Knosalla C,Hippenstiel S,Reinke P,Kurtz A
Sun Mar 01 00:00:00 UTC 2020
Endothelial Progenitor Cells Produced From Human Pluripotent Stem Cells by a Synergistic Combination of Cytokines, Small Compounds, and Serum-Free Medium.
Frontiers in cell and developmental biology
Farkas S,Simara P,Rehakova D,Veverkova L,Koutna I
100-20 was used in In vitro experiments to devise a robust three-phase protocol exploiting the synergy of multiple differentiation effector to efficently convert hPSCs into EPCs.
Mon Sep 28 00:00:00 UTC 2020
Resolving the fibrotic niche of human liver cirrhosis at single-cell level.
Nature
Ramachandran P,Dobie R,Wilson-Kanamori JR,Dora EF,Henderson BEP,Luu NT,Portman JR,Matchett KP,Brice M,Marwick JA,Taylor RS,Efremova M,Vento-Tormo R,Carragher NO,Kendall TJ,Fallowfield JA,Harrison EM,Mole DJ,Wigmore SJ,Newsome PN,Weston CJ,Iredale JP,Tacke F,Pollard JW,Ponting CP,Marioni JC,Teichmann SA,Henderson NC
100-20 was used in In vitro experiments to investigate molecular definitions for non-parenchymal cell types in the healthy and cirrhotic human liver through transcriptomics.
Fri Nov 01 00:00:00 UTC 2019
Human blood vessel organoids as a model of diabetic vasculopathy.
Nature
Wimmer RA,Leopoldi A,Aichinger M,Wick N,Hantusch B,Novatchkova M,Taubenschmid J,Hämmerle M,Esk C,Bagley JA,Lindenhofer D,Chen G,Boehm M,Agu CA,Yang F,Fu B,Zuber J,Knoblich JA,Kerjaschki D,Penninger JM
Tue Jan 01 00:00:00 UTC 2019
Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.
The Journal of clinical investigation
Iring A,Jin YJ,Albarrán-Juárez J,Siragusa M,Wang S,Dancs PT,Nakayama A,Tonack S,Chen M,Künne C,Sokol AM,Günther S,Martínez A,Fleming I,Wettschureck N,Graumann J,Weinstein LS,Offermanns S
Mon Jun 17 00:00:00 UTC 2019
The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.
The EMBO journal
Sainz de Aja J,Menchero S,Rollan I,Barral A,Tiana M,Jawaid W,Cossio I,Alvarez A,Carreño-Tarragona G,Badia-Careaga C,Nichols J,Göttgens B,Isern J,Manzanares M
Mon Apr 01 00:00:00 UTC 2019
Restoration of FVIII expression by targeted gene insertion in the FVIII locus in hemophilia A patient-derived iPSCs.
Experimental & molecular medicine
Sung JJ,Park CY,Leem JW,Cho MS,Kim DW
Wed Apr 17 00:00:00 UTC 2019
Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering.
Experimental & molecular medicine
Jang Y,Choi J,Park N,Kang J,Kim M,Kim Y,Ju JH
Mon Jan 07 00:00:00 UTC 2019
Novel human Ab against vascular endothelial growth factor receptor 2 shows therapeutic potential for leukemia and prostate cancer.
Cancer science
Lu RM,Chiu CY,Liu IJ,Chang YL,Liu YJ,Wu HC
Sun Dec 01 00:00:00 UTC 2019
Novel human Ab against vascular endothelial growth factor receptor 2 shows therapeutic potential for leukemia and prostate cancer.
Cancer science
Lu RM,Chiu CY,Liu IJ,Chang YL,Liu YJ,Wu HC
Sun Dec 01 00:00:00 UTC 2019
First trimester placental endothelial cells from pregnancies with abnormal uterine artery Doppler are more sensitive to apoptotic stimuli.
Laboratory investigation; a journal of technical methods and pathology
Charolidi N,Host AJ,Ashton S,Tryfonos Z,Leslie K,Thilaganathan B,Cartwright JE,Whitley GS
Fri Mar 01 00:00:00 UTC 2019
Anti-angiogenic effect of quercetin and its 8-methyl pentamethyl ether derivative in human microvascular endothelial cells.
Journal of cellular and molecular medicine
Lupo G,Cambria MT,Olivieri M,Rocco C,Caporarello N,Longo A,Zanghì G,Salmeri M,Foti MC,Anfuso CD
Tue Oct 01 00:00:00 UTC 2019
Phorbol esters induce PLVAP expression via VEGF and additional secreted molecules in MEK1-dependent and p38, JNK and PI3K/Akt-independent manner.
Journal of cellular and molecular medicine
Hamilton BJ,Tse D,Stan RV
Fri Feb 01 00:00:00 UTC 2019
Neutrophil activation in systemic capillary leak syndrome (Clarkson disease).
Journal of cellular and molecular medicine
Xie Z,Kuhns DB,Gu X,Otu HH,Libermann TA,Gallin JI,Parikh SM,Druey KM
Thu Aug 01 00:00:00 UTC 2019
iPSC-Derived Brain Endothelium Exhibits Stable, Long-Term Barrier Function in Perfused Hydrogel Scaffolds.
Stem cell reports
Faley SL,Neal EH,Wang JX,Bosworth AM,Weber CM,Balotin KM,Lippmann ES,Bellan LM
Tue Mar 05 00:00:00 UTC 2019
The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis.
Scientific reports
Dimou P,Wright RD,Budge KL,Midgley A,Satchell SC,Peak M,Beresford MW
Thu Jun 06 00:00:00 UTC 2019
Cell Type-Specific Interferon-γ-mediated Antagonism of KSHV Lytic Replication.
Scientific reports
Park MK,Cho H,Roh SW,Kim SJ,Myoung J
Wed Feb 20 00:00:00 UTC 2019
Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells.
Stem cell reports
Praça C,Rosa SC,Sevin E,Cecchelli R,Dehouck MP,Ferreira LS
Tue Oct 08 00:00:00 UTC 2019
Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury.
Scientific reports
Shiga Y,Shiga A,Mesci P,Kwon H,Brifault C,Kim JH,Jeziorski JJ,Nasamran C,Ohtori S,Muotri AR,Gonias SL,Campana WM
Tue Dec 17 00:00:00 UTC 2019
Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury.
Scientific reports
Shiga Y,Shiga A,Mesci P,Kwon H,Brifault C,Kim JH,Jeziorski JJ,Nasamran C,Ohtori S,Muotri AR,Gonias SL,Campana WM
Tue Dec 17 00:00:00 UTC 2019
Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury.
Scientific reports
Shiga Y,Shiga A,Mesci P,Kwon H,Brifault C,Kim JH,Jeziorski JJ,Nasamran C,Ohtori S,Muotri AR,Gonias SL,Campana WM
Tue Dec 17 00:00:00 UTC 2019
Vascular leakage caused by loss of Akt1 is associated with impaired mural cell coverage.
FEBS open bio
Ha JM,Jin SY,Lee HS,Vafaeinik F,Jung YJ,Keum HJ,Song SH,Lee DH,Kim CD,Bae SS
Mon Apr 01 00:00:00 UTC 2019
Vascular leakage caused by loss of Akt1 is associated with impaired mural cell coverage.
FEBS open bio
Ha JM,Jin SY,Lee HS,Vafaeinik F,Jung YJ,Keum HJ,Song SH,Lee DH,Kim CD,Bae SS
Mon Apr 01 00:00:00 UTC 2019
Calpain Inhibition Restores Autophagy and Prevents Mitochondrial Fragmentation in a Human iPSC Model of Diabetic Endotheliopathy.
Stem cell reports
Ong SB,Lee WH,Shao NY,Ismail NI,Katwadi K,Lim MM,Kwek XY,Michel NA,Li J,Newson J,Tahmasebi S,Rehman J,Kodo K,Jang HR,Ong SG
Tue Mar 05 00:00:00 UTC 2019
Pericytes Contribute to Dysfunction in a Human 3D Model of Placental Microvasculature through VEGF-Ang-Tie2 Signaling.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Haase K,Gillrie MR,Hajal C,Kamm RD
Sun Dec 01 00:00:00 UTC 2019
Generation of blood vessel organoids from human pluripotent stem cells.
Nature protocols
Wimmer RA,Leopoldi A,Aichinger M,Kerjaschki D,Penninger JM
100-20 was used in In vitro experiments to describe a protocol to generate self-organizing 3D human blood vessel organoids from hPSCs that exhibit morphological, functional and molecular features of human microvasculature.
Fri Nov 01 00:00:00 UTC 2019
Iron deficiency disrupts embryonic haematopoiesis but not the endothelial to haematopoietic transition.
Scientific reports
Shvartsman M,Bilican S,Lancrin C
Tue Apr 23 00:00:00 UTC 2019
Sex-dependent VEGF expression underlies variations in human pluripotent stem cell to endothelial progenitor differentiation.
Scientific reports
Randolph LN,Bao X,Oddo M,Lian XL
Wed Nov 13 00:00:00 UTC 2019
A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity.
Current protocols in stem cell biology
Rosa S,Pitrez P,Fernandes H,Ferreira L
100-20 was used in In vitro experiments to describe a screening platform to identify compounds that affect human embryonic vascular development.
Sun Sep 01 00:00:00 UTC 2019
High mitogenic stimulation arrests angiogenesis.
Nature communications
Pontes-Quero S,Fernández-Chacón M,Luo W,Lunella FF,Casquero-Garcia V,Garcia-Gonzalez I,Hermoso A,Rocha SF,Bansal M,Benedito R
Wed May 01 00:00:00 UTC 2019
High mitogenic stimulation arrests angiogenesis.
Nature communications
Pontes-Quero S,Fernández-Chacón M,Luo W,Lunella FF,Casquero-Garcia V,Garcia-Gonzalez I,Hermoso A,Rocha SF,Bansal M,Benedito R
Wed May 01 00:00:00 UTC 2019
Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts.
Nature communications
Redd MA,Zeinstra N,Qin W,Wei W,Martinson A,Wang Y,Wang RK,Murry CE,Zheng Y
Mon Feb 04 00:00:00 UTC 2019
Functional characterization of iPSC-derived arterial- and venous-like endothelial cells.
Scientific reports
Rosa S,Praça C,Pitrez PR,Gouveia PJ,Aranguren XL,Ricotti L,Ferreira LS
Thu Mar 07 00:00:00 UTC 2019
PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia.
Stem cell reports
Konttinen H,Cabral-da-Silva MEC,Ohtonen S,Wojciechowski S,Shakirzyanova A,Caligola S,Giugno R,Ishchenko Y,Hernández D,Fazaludeen MF,Eamen S,Budia MG,Fagerlund I,Scoyni F,Korhonen P,Huber N,Haapasalo A,Hewitt AW,Vickers J,Smith GC,Oksanen M,Graff C,Kanninen KM,Lehtonen S,Propson N,Schwartz MP,Pébay A,Koistinaho J,Ooi L,Malm T
Tue Oct 08 00:00:00 UTC 2019
Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis.
Acta neuropathologica communications
Gomez-Giro G,Arias-Fuenzalida J,Jarazo J,Zeuschner D,Ali M,Possemis N,Bolognin S,Halder R,Jäger C,Kuper WFE,van Hasselt PM,Zaehres H,Del Sol A,van der Putten H,Schöler HR,Schwamborn JC
100-20 was used in Cell Culture to suggest that a mutation in CLN3 severely affects brain development.
Mon Dec 30 00:00:00 UTC 2019
Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures.
Stem cell reports
Kelleher J,Dickinson A,Cain S,Hu Y,Bates N,Harvey A,Ren J,Zhang W,Moreton FC,Muir KW,Ward C,Touyz RM,Sharma P,Xu Q,Kimber SJ,Wang T
Tue Nov 12 00:00:00 UTC 2019
Transplantation of human endometrial perivascular cells with elevated CYR61 expression induces angiogenesis and promotes repair of a full-thickness uterine injury in rat.
Stem cell research & therapy
Li Z,Yan G,Diao Q,Yu F,Li X,Sheng X,Liu Y,Dai Y,Zhou H,Zhen X,Hu Y,Péault B,Ding L,Sun H,Li H
100-20 was used in In vitro experiments to indicate that En-PSCs with elevated CYR61 expression loaded on a collagen scaffold may support uterine tissue regeneration.
Tue Jun 18 00:00:00 UTC 2019
A fully human transgene switch to regulate therapeutic protein production by cooling sensation.
Nature medicine
Bai P,Liu Y,Xue S,Hamri GC,Saxena P,Ye H,Xie M,Fussenegger M
100-20 was used in In vitro experiments to control transgene expression by harnessing signaling pathway controlled by human transient receptor potential (TRP) melastatin 8 (hTRPM8), a TRP channel family member1.
Thu Aug 01 00:00:00 UTC 2019
Intrinsic Immunity Shapes Viral Resistance of Stem Cells.
Cell
Wu X,Dao Thi VL,Huang Y,Billerbeck E,Saha D,Hoffmann HH,Wang Y,Silva LAV,Sarbanes S,Sun T,Andrus L,Yu Y,Quirk C,Li M,MacDonald MR,Schneider WM,An X,Rosenberg BR,Rice CM
Thu Jan 25 00:00:00 UTC 2018
Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production.
Cell
Longchamp A,Mirabella T,Arduini A,MacArthur MR,Das A,Treviño-Villarreal JH,Hine C,Ben-Sahra I,Knudsen NH,Brace LE,Reynolds J,Mejia P,Tao M,Sharma G,Wang R,Corpataux JM,Haefliger JA,Ahn KH,Lee CH,Manning BD,Sinclair DA,Chen CS,Ozaki CK,Mitchell JR
Thu Mar 22 00:00:00 UTC 2018
Generation and post-injury integration of human spinal cord neural stem cells.
Nature methods
Kumamaru H,Kadoya K,Adler AF,Takashima Y,Graham L,Coppola G,Tuszynski MH
Sat Sep 01 00:00:00 UTC 2018
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping.
Cell stem cell
Czerniecki SM,Cruz NM,Harder JL,Menon R,Annis J,Otto EA,Gulieva RE,Islas LV,Kim YK,Tran LM,Martins TJ,Pippin JW,Fu H,Kretzler M,Shankland SJ,Himmelfarb J,Moon RT,Paragas N,Freedman BS
100-20 was used in Cell Culture to conclude that organoids in HTS formats thus establish an attractive platform for multidimensional phenotypic screening.
Fri Jun 01 00:00:00 UTC 2018
Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration.
Proceedings of the National Academy of Sciences of the United States of America
Kim MC,Silberberg YR,Abeyaratne R,Kamm RD,Asada HH
Tue Jan 16 00:00:00 UTC 2018
Human Urine-Derived Stem Cell Differentiation to Endothelial Cells with Barrier Function and Nitric Oxide Production.
Stem cells translational medicine
Liu G,Wu R,Yang B,Deng C,Lu X,Walker SJ,Ma PX,Mou S,Atala A,Zhang Y
Sat Sep 01 00:00:00 UTC 2018
Quality-Quantity Control Culture Enhances Vasculogenesis and Wound Healing Efficacy of Human Diabetic Peripheral Blood CD34+ Cells.
Stem cells translational medicine
Tanaka R,Masuda H,Fujimura S,Ito-Hirano R,Arita K,Kakinuma Y,Hagiwara H,Kado M,Hayashi A,Mita T,Ogawa T,Watada H,Mizuno H,Sawada N,Asahara T
Tue May 01 00:00:00 UTC 2018
Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic Activities.
Journal of immunology (Baltimore, Md. : 1950)
Lavoie SS,Dumas E,Vulesevic B,Neagoe PE,White M,Sirois MG
Fri Jun 01 00:00:00 UTC 2018
Improved Left Ventricular Aneurysm Repair with Cell- and Cytokine-Seeded Collagen Patches.
Stem cells international
Qu H,Xie BD,Wu J,Lv B,Chuai JB,Li JZ,Cai J,Wu H,Jiang SL,Leng XP,Kang K
100-20 was used in In vitro experiments to determine methods of vascularising engineered heart tissue following treatment for surgical ventricular restoration.
Wed Mar 16 00:00:00 UTC 2022
Cryopreservation of canine cardiosphere-derived cells: Implications for clinical application.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Dutton LC,Church SAV,Hodgkiss-Geere H,Catchpole B,Huggins A,Dudhia J,Connolly DJ
100-20 was used in Cell Culture to show that cryopreservation of canine CDCs is feasible without altering their stem characteristics, thereby facilitating their utilization for clinical trials.
Mon Jan 01 00:00:00 UTC 2018
Control of endothelial cell polarity and sprouting angiogenesis by non-centrosomal microtubules.
eLife
Martin M,Veloso A,Wu J,Katrukha EA,Akhmanova A
100-20 was used in Cell Culture to show that centrosome loss had no effect on the ability of endothelial cells to polarize and move in 2D and 3D environments.
Fri Mar 16 00:00:00 UTC 2018
MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1.
Stem cell reports
Wang H,Liu C,Liu X,Wang M,Wu D,Gao J,Su P,Nakahata T,Zhou W,Xu Y,Shi L,Ma F,Zhou J
Tue Feb 13 00:00:00 UTC 2018
Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.
Scientific reports
Acosta MI,Urbach S,Doye A,Ng YW,Boudeau J,Mettouchi A,Debant A,Manser E,Visvikis O,Lemichez E
Tue Jan 23 00:00:00 UTC 2018
MicroRNA regulation of the MRN complex impacts DNA damage, cellular senescence, and angiogenic signaling.
Cell death & disease
Espinosa-Diez C,Wilson R,Chatterjee N,Hudson C,Ruhl R,Hipfinger C,Helms E,Khan OF,Anderson DG,Anand S
Thu May 24 00:00:00 UTC 2018
Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration.
Stem cell research & therapy
Zhang W,Chu W,Liu Q,Coates D,Shang Y,Li C
100-20 was used in In vitro experiments to report the expression, functions, and molecular interactions of deer thymosin beta 10 (TMSB10) in tissue and cells in antler growth.
Tue Jun 19 00:00:00 UTC 2018
NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells.
Nature communications
Uenishi GI,Jung HS,Kumar A,Park MA,Hadland BK,McLeod E,Raymond M,Moskvin O,Zimmerman CE,Theisen DJ,Swanson S,J Tamplin O,Zon LI,Thomson JA,Bernstein ID,Slukvin II
Tue May 08 00:00:00 UTC 2018
A Scalable and Efficient Bioprocess for Manufacturing Human Pluripotent Stem Cell-Derived Endothelial Cells.
Stem cell reports
Lin H,Du Q,Li Q,Wang O,Wang Z,Sahu N,Elowsky C,Liu K,Zhang C,Chung S,Duan B,Lei Y
Tue Aug 14 00:00:00 UTC 2018
Soluble cMet levels in urine are a significant prognostic biomarker for diabetic nephropathy.
Scientific reports
Kim YC,An JN,Kim JH,Choi YW,Oh S,Kwon SH,Lee MY,Lee J,Jeong JG,Lim CS,Kim YS,Yang SH,Lee JP
Fri Aug 24 00:00:00 UTC 2018
FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.
eLife
Künzel U,Grieve AG,Meng Y,Sieber B,Cowley SA,Freeman M
100-20 was used in Cell Culture to examine the role of ADAM17 in the regulated release of multiple cytokine and growth factor signals.
Wed Jun 13 00:00:00 UTC 2018
RXRα provokes tumor suppression through p53/p21/p16 and PI3K-AKT signaling pathways during stem cell differentiation and in cancer cells.
Cell death & disease
Zhang R,Li H,Zhang S,Zhang Y,Wang N,Zhou H,He H,Hu G,Zhang TC,Ma W
Tue May 01 00:00:00 UTC 2018
Large-scale production of megakaryocytes in microcarrier-supported stirred suspension bioreactors.
Scientific reports
Eicke D,Baigger A,Schulze K,Latham SL,Halloin C,Zweigerdt R,Guzman CA,Blasczyk R,Figueiredo C
Thu Jul 05 00:00:00 UTC 2018
Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro.
Stem cell reports
Garcia-Alegria E,Menegatti S,Fadlullah MZH,Menendez P,Lacaud G,Kouskoff V
Tue Nov 13 00:00:00 UTC 2018
Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription.
Cell discovery
Wang H,Lapek J,Fujimura K,Strnadel J,Liu B,Gonzalez DJ,Zhang W,Watson F,Yu V,Liu C,Melo CM,Miller YI,Elliott KC,Cheresh DA,Klemke RL
Thu Oct 01 00:00:00 UTC 2020
iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors.
Cell death & disease
Melguizo-Sanchis D,Xu Y,Taheem D,Yu M,Tilgner K,Barta T,Gassner K,Anyfantis G,Wan T,Elango R,Alharthi S,El-Harouni AA,Przyborski S,Adam S,Saretzki G,Samarasinghe S,Armstrong L,Lako M
Fri Jan 26 00:00:00 UTC 2018
Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy.
Cell death & disease
Piñol-Jurado P,Suárez-Calvet X,Fernández-Simón E,Gallardo E,de la Oliva N,Martínez-Muriana A,Gómez-Gálvez P,Escudero LM,Pérez-Peiró M,Wollin L,de Luna N,Navarro X,Illa I,Díaz-Manera J
Tue Jul 10 00:00:00 UTC 2018
Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells.
Scientific reports
MacLean GA,McEldoon J,Huang J,Allred J,Canver MC,Orkin SH
Tue May 22 00:00:00 UTC 2018
FLI1 and PKC co-activation promote highly efficient differentiation of human embryonic stem cells into endothelial-like cells.
Cell death & disease
Zhao H,Zhao Y,Li Z,Ouyang Q,Sun Y,Zhou D,Xie P,Zeng S,Dong L,Wen H,Lu G,Lin G,Hu L
Fri Jan 26 00:00:00 UTC 2018
ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells.
iScience
Hofsteen P,Robitaille AM,Strash N,Palpant N,Moon RT,Pabon L,Murry CE
100-20 was used in Cell Culture to study how Alpha Protein Kinase 2 (ALPK2) is a candidate negative regulator of WNT/β-catenin signaling in cardiogenesis and that ALPK2 regulates β-catenin-dependent signaling during developmental commitment of cardiomyocytes.
Fri Apr 27 00:00:00 UTC 2018
Prostaglandin E2 Is Required for BMP4-Induced Mesoderm Differentiation of Human Embryonic Stem Cells.
Stem cell reports
Zhang B,He L,Liu Y,Zhang J,Zeng Q,Wang S,Fan Z,Fang F,Chen L,Lv Y,Xi J,Yue W,Li Y,Pei X
Tue Mar 13 00:00:00 UTC 2018
Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells.
Stem cell reports
Kauts ML,De Leo B,Rodríguez-Seoane C,Ronn R,Glykofrydis F,Maglitto A,Kaimakis P,Basi M,Taylor H,Forrester L,Wilkinson AC,Göttgens B,Saunders P,Dzierzak E
Tue Oct 09 00:00:00 UTC 2018
Transplantation of iPS-Derived Tumor Cells with a Homozygous MHC Haplotype Induces GRP94 Antibody Production in MHC-Matched Macaques.
Cancer research
Ishigaki H,Maeda T,Inoue H,Akagi T,Sasamura T,Ishida H,Inubushi T,Okahara J,Shiina T,Nakayama M,Itoh Y,Ogasawara K
100-20 was used in Cell Culture to demonstrate that autoantibodies can mitigate tumour growth in vitro and in vivo.
Wed Nov 01 00:00:00 UTC 2017
Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification.
Cell death and differentiation
Vicinanza C,Aquila I,Scalise M,Cristiano F,Marino F,Cianflone E,Mancuso T,Marotta P,Sacco W,Lewis FC,Couch L,Shone V,Gritti G,Torella A,Smith AJ,Terracciano CM,Britti D,Veltri P,Indolfi C,Nadal-Ginard B,Ellison-Hughes GM,Torella D
Fri Dec 01 00:00:00 UTC 2017
Insertion of scFv into the hinge domain of full-length IgG1 monoclonal antibody results in tetravalent bispecific molecule with robust properties.
mAbs
Bezabeh B,Fleming R,Fazenbaker C,Zhong H,Coffman K,Yu XQ,Leow CC,Gibson N,Wilson S,Stover CK,Wu H,Gao C,Dimasi N
100-20 was used in Enzyme-linked immunosorbent assay to characterize Bs4Ab, an innovative and generic bispecific tetravalent antibody platform.
Tue Nov 28 00:00:00 UTC 2017
Angiogenic conditioning of peripheral blood mononuclear cells promotes fracture healing.
Bone & joint research
Mifuji K,Ishikawa M,Kamei N,Tanaka R,Arita K,Mizuno H,Asahara T,Adachi N,Ochi M
100-20 was used in Cell Culture to demonstrate that QQMNCs have superior potential to accelerate fracture healing compared with PBMNCs. The QQMNCs could be a promising option for fracture nonunion.
Tue Aug 01 00:00:00 UTC 2017
An Optimized 3D Coculture Assay for Preclinical Testing of Pro- and Antiangiogenic Drugs.
SLAS discovery : advancing life sciences R & D
Unterleuthner D,Kramer N,Pudelko K,Burian A,Hengstschläger M,Dolznig H
100-20 was used in In vitro experiments to investigate methods of preventing angiogenesis.
Thu Jun 01 00:00:00 UTC 2017
An Optimized 3D Coculture Assay for Preclinical Testing of Pro- and Antiangiogenic Drugs.
SLAS discovery : advancing life sciences R & D
Unterleuthner D,Kramer N,Pudelko K,Burian A,Hengstschläger M,Dolznig H
100-20 was used in In vitro experiments to investigate methods of preventing angiogenesis.
Thu Jun 01 00:00:00 UTC 2017
Cell sex affects extracellular matrix protein expression and proliferation of smooth muscle progenitor cells derived from human pluripotent stem cells.
Stem cell research & therapy
Li Y,Wen Y,Green M,Cabral EK,Wani P,Zhang F,Wei Y,Baer TM,Chen B
100-20 was used in Cell Culture to explore differences in stem cell differentiation between male and female human pluripotent stem cells (hPSCs) and the effect of oestrogen on hPSC-derived smooth muscle progenitor cells.
Tue Jul 04 00:00:00 UTC 2017
Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis.
The Journal of biological chemistry
Suh JH,Lai L,Nam D,Kim J,Jo J,Taffet GE,Kim E,Kaelber JT,Lee HK,Entman ML,Cooke JP,Reineke EL
Fri Dec 29 00:00:00 UTC 2017
Bone marrow mesenchymal stem cells combine with Treated dentin matrix to build biological root.
Scientific reports
Luo S,Pei F,Zhang W,Guo W,Li R,He W,Tian W
Wed Apr 12 00:00:00 UTC 2017
Sex-specific eNOS activity and function in human endothelial cells.
Scientific reports
Cattaneo MG,Vanetti C,Decimo I,Di Chio M,Martano G,Garrone G,Bifari F,Vicentini LM
Tue Aug 29 00:00:00 UTC 2017
Modeling cadmium-induced endothelial toxicity using human pluripotent stem cell-derived endothelial cells.
Scientific reports
Tang L,Su J,Liang P
Wed Nov 01 00:00:00 UTC 2017
Methylseleninic Acid Provided at Nutritional Selenium Levels Inhibits Angiogenesis by Down-regulating Integrin β3 Signaling.
Scientific reports
Cai Z,Dong L,Song C,Zhang Y,Zhu C,Zhang Y,Ling Q,Hoffmann PR,Li J,Huang Z,Li W
Fri Aug 25 00:00:00 UTC 2017
Methylseleninic Acid Provided at Nutritional Selenium Levels Inhibits Angiogenesis by Down-regulating Integrin β3 Signaling.
Scientific reports
Cai Z,Dong L,Song C,Zhang Y,Zhu C,Zhang Y,Ling Q,Hoffmann PR,Li J,Huang Z,Li W
Fri Aug 25 00:00:00 UTC 2017
Bioinspired Heparin Nanosponge Prepared by Photo-crosslinking for Controlled Release of Growth Factors.
Scientific reports
Choi WI,Sahu A,Vilos C,Kamaly N,Jo SM,Lee JH,Tae G
Mon Oct 30 00:00:00 UTC 2017
Differentiation of Human Induced Pluripotent Stem Cells (iPS Cells) and Embryonic Stem Cells (ES Cells) into Dendritic Cell (DC) Subsets.
Bio-protocol
Sontag S,Förster M,Seré K,Zenke M
100-20 was used in Sample Preparation to study subset specification and function of human dendritic cells (DCs) using a protocol which generates classical cDC1, classical cDC2 and plasmacytoid pDC in vitro from human induced pluripotent stem cells (iPS) cells or ES cells.
Sat Aug 05 00:00:00 UTC 2017
A protein interaction mechanism for suppressing the mechanosensitive Piezo channels.
Nature communications
Zhang T,Chi S,Jiang F,Zhao Q,Xiao B
Mon Nov 27 00:00:00 UTC 2017
Downregulation of LGR5 Expression Inhibits Cardiomyocyte Differentiation and Potentiates Endothelial Differentiation from Human Pluripotent Stem Cells.
Stem cell reports
Jha R,Singh M,Wu Q,Gentillon C,Preininger MK,Xu C
Tue Aug 08 00:00:00 UTC 2017
Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents.
Nature communications
Cho CF,Wolfe JM,Fadzen CM,Calligaris D,Hornburg K,Chiocca EA,Agar NYR,Pentelute BL,Lawler SE
100-20 was used in Cell Culture to report that self-assembling multicellular BBB spheroids display reproducible BBB features and functions.
Tue Jun 06 00:00:00 UTC 2017
SCARF-1 promotes adhesion of CD4+ T cells to human hepatic sinusoidal endothelium under conditions of shear stress.
Scientific reports
Patten DA,Kamarajah SK,Rose JM,Tickle J,Shepherd EL,Adams DH,Weston CJ,Shetty S
Thu Dec 14 00:00:00 UTC 2017
A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.
Stem cell reports
Haenseler W,Sansom SN,Buchrieser J,Newey SE,Moore CS,Nicholls FJ,Chintawar S,Schnell C,Antel JP,Allen ND,Cader MZ,Wade-Martins R,James WS,Cowley SA
Tue Jun 06 00:00:00 UTC 2017
Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.
Cell stem cell
Kotini AG,Chang CJ,Chow A,Yuan H,Ho TC,Wang T,Vora S,Solovyov A,Husser C,Olszewska M,Teruya-Feldstein J,Perumal D,Klimek VM,Spyridonidis A,Rampal RK,Silverman L,Reddy EP,Papaemmanuil E,Parekh S,Greenbaum BD,Leslie CS,Kharas MG,Papapetrou EP
100-20 was used in Cell Culture to provide insight into the cellular events demarcating the initiation and progression of myeloid transformation and a new platform for testing genetic and pharmacological interventions.
Thu Mar 02 00:00:00 UTC 2017
Neuropilin 1 binds PDGF-D and is a co-receptor in PDGF-D-PDGFRβ signaling.
Journal of cell science
Muhl L,Folestad EB,Gladh H,Wang Y,Moessinger C,Jakobsson L,Eriksson U
100-20 was used in Cell Culture to show that NRP1 can act as a co-receptor for PDGF-D-PDGFRβ signaling and is possibly implicated in intercellular communication in the vascular wall.
Sat Apr 15 00:00:00 UTC 2017
Androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of renal cell carcinoma.
Nature communications
Huang Q,Sun Y,Ma X,Gao Y,Li X,Niu Y,Zhang X,Chang C
Fri Oct 13 00:00:00 UTC 2017
Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition.
Nature communications
Aday S,Zoldan J,Besnier M,Carreto L,Saif J,Fernandes R,Santos T,Bernardino L,Langer R,Emanueli C,Ferreira L
Fri Sep 29 00:00:00 UTC 2017
Colloidal Gels with Extracellular Matrix Particles and Growth Factors for Bone Regeneration in Critical Size Rat Calvarial Defects.
The AAPS journal
Townsend JM,Dennis SC,Whitlow J,Feng Y,Wang J,Andrews B,Nudo RJ,Detamore MS,Berkland CJ
100-20 was used in In vitro experiments to study the development of a novel colloidal gel as a commercially available product for craniofacial reconstruction.
Mon May 01 00:00:00 UTC 2017
c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma.
The Journal of clinical investigation
Huang M,Liu T,Ma P,Mitteer RA,Zhang Z,Kim HJ,Yeo E,Zhang D,Cai P,Li C,Zhang L,Zhao B,Roccograndi L,O'Rourke DM,Dahmane N,Gong Y,Koumenis C,Fan Y
Mon May 02 00:00:00 UTC 2016
Senp1 drives hypoxia-induced polycythemia via GATA1 and Bcl-xL in subjects with Monge's disease.
The Journal of experimental medicine
Azad P,Zhao HW,Cabrales PJ,Ronen R,Zhou D,Poulsen O,Appenzeller O,Hsiao YH,Bafna V,Haddad GG
Mon Nov 14 00:00:00 UTC 2016
Dual Therapeutic Action of a Neutralizing Anti-FGF2 Aptamer in Bone Disease and Bone Cancer Pain.
Molecular therapy : the journal of the American Society of Gene Therapy
Jin L,Nonaka Y,Miyakawa S,Fujiwara M,Nakamura Y
Tue Nov 01 00:00:00 UTC 2016
Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity.
Proceedings of the National Academy of Sciences of the United States of America
Wentink MQ,Hackeng TM,Tabruyn SP,Puijk WC,Schwamborn K,Altschuh D,Meloen RH,Schuurman T,Griffioen AW,Timmerman P
Tue Nov 01 00:00:00 UTC 2016
Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity.
Proceedings of the National Academy of Sciences of the United States of America
Wentink MQ,Hackeng TM,Tabruyn SP,Puijk WC,Schwamborn K,Altschuh D,Meloen RH,Schuurman T,Griffioen AW,Timmerman P
Tue Nov 01 00:00:00 UTC 2016
Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation.
Journal of lipid research
Oh MJ,Zhang C,LeMaster E,Adamos C,Berdyshev E,Bogachkov Y,Kohler EE,Baruah J,Fang Y,Schraufnagel DE,Wary KK,Levitan I
Sun May 01 00:00:00 UTC 2016
Knockdown of DNMT1 and DNMT3a Promotes the Angiogenesis of Human Mesenchymal Stem Cells Leading to Arterial Specific Differentiation.
Stem cells (Dayton, Ohio)
Zhang R,Wang N,Zhang LN,Huang N,Song TF,Li ZZ,Li M,Luo XG,Zhou H,He HP,Zhang XY,Ma W,Zhang TC
Sun May 01 00:00:00 UTC 2016
β-Globin-Expressing Definitive Erythroid Progenitor Cells Generated from Embryonic and Induced Pluripotent Stem Cell-Derived Sacs.
Stem cells (Dayton, Ohio)
Fujita A,Uchida N,Haro-Mora JJ,Winkler T,Tisdale J
Wed Jun 01 00:00:00 UTC 2016
β-Globin-Expressing Definitive Erythroid Progenitor Cells Generated from Embryonic and Induced Pluripotent Stem Cell-Derived Sacs.
Stem cells (Dayton, Ohio)
Fujita A,Uchida N,Haro-Mora JJ,Winkler T,Tisdale J
Wed Jun 01 00:00:00 UTC 2016
VEGF Requires the Receptor NRP-1 To Inhibit Lipopolysaccharide-Dependent Dendritic Cell Maturation.
Journal of immunology (Baltimore, Md. : 1950)
Oussa NA,Dahmani A,Gomis M,Richaud M,Andreev E,Navab-Daneshmand AR,Taillefer J,Carli C,Boulet S,Sabbagh L,Labrecque N,Sapieha P,Delisle JS
Tue Nov 15 00:00:00 UTC 2016
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways.
Oncology reports
Ma K,Wang C,Geng Q,Fan Y,Ning J,Yang H,Dong X,Dong D,Guo Y,Wei X,Li E,Wu Y
100-20 was used in Sample Preparation to suggest that rAAV2-anginex may inhibit tumor angiogenesis and growth through regulating Akt, JNK and NF-κB signaling pathways.
Wed Jun 01 00:00:00 UTC 2016
Macrophages form functional vascular mimicry channels in vivo.
Scientific reports
Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M
Fri Nov 11 00:00:00 UTC 2016
Co-delivery of VEGF and bFGF via a PLGA nanoparticle-modified BAM for effective contracture inhibition of regenerated bladder tissue in rabbits.
Scientific reports
Jiang X,Lin H,Jiang D,Xu G,Fang X,He L,Xu M,Tang B,Wang Z,Cui D,Chen F,Geng H
Mon Feb 08 00:00:00 UTC 2016
Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.
Cell death & disease
Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M
Thu Jul 28 00:00:00 UTC 2016
GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells.
Stem cell reports
D'Souza SS,Maufort J,Kumar A,Zhang J,Smuga-Otto K,Thomson JA,Slukvin II
Tue Feb 09 00:00:00 UTC 2016
Erianin inhibits high glucose-induced retinal angiogenesis via blocking ERK1/2-regulated HIF-1α-VEGF/VEGFR2 signaling pathway.
Scientific reports
Yu Z,Zhang T,Gong C,Sheng Y,Lu B,Zhou L,Ji L,Wang Z
Wed Sep 28 00:00:00 UTC 2016
Erianin inhibits high glucose-induced retinal angiogenesis via blocking ERK1/2-regulated HIF-1α-VEGF/VEGFR2 signaling pathway.
Scientific reports
Yu Z,Zhang T,Gong C,Sheng Y,Lu B,Zhou L,Ji L,Wang Z
Wed Sep 28 00:00:00 UTC 2016
Novel Interaction Mechanism of a Domain Antibody-based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency than Ranibizumab and Bevacizumab and Improved Capacity over Aflibercept.
The Journal of biological chemistry
Walker A,Chung CW,Neu M,Burman M,Batuwangala T,Jones G,Tang CM,Steward M,Mullin M,Tournier N,Lewis A,Korczynska J,Chung V,Catchpole I
Fri Mar 11 00:00:00 UTC 2016
Intrinsic FGF2 and FGF5 promotes angiogenesis of human aortic endothelial cells in 3D microfluidic angiogenesis system.
Scientific reports
Seo HR,Jeong HE,Joo HJ,Choi SC,Park CY,Kim JH,Choi JH,Cui LH,Hong SJ,Chung S,Lim DS
Thu Jun 30 00:00:00 UTC 2016
NPNT is Expressed by Osteoblasts and Mediates Angiogenesis via the Activation of Extracellular Signal-regulated Kinase.
Scientific reports
Kuek V,Yang Z,Chim SM,Zhu S,Xu H,Chow ST,Tickner J,Rosen V,Erber W,Li X,Qin A,Qian Y,Xu J
Wed Oct 26 00:00:00 UTC 2016
The anti-angiogenic effect and novel mechanisms of action of Combretastatin A-4.
Scientific reports
Su M,Huang J,Liu S,Xiao Y,Qin X,Liu J,Pi C,Luo T,Li J,Chen X,Luo Z
Fri Jun 24 00:00:00 UTC 2016
Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models.
Scientific reports
Ameku T,Taura D,Sone M,Numata T,Nakamura M,Shiota F,Toyoda T,Matsui S,Araoka T,Yasuno T,Mae S,Kobayashi H,Kondo N,Kitaoka F,Amano N,Arai S,Ichisaka T,Matsuura N,Inoue S,Yamamoto T,Takahashi K,Asaka I,Yamada Y,Ubara Y,Muso E,Fukatsu A,Watanabe A,Sato Y,Nakahata T,Mori Y,Koizumi A,Nakao K,Yamanaka S,Osafune K
Fri Jul 15 00:00:00 UTC 2016
Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans.
Blood
Massena S,Christoffersson G,Vågesjö E,Seignez C,Gustafsson K,Binet F,Herrera Hidalgo C,Giraud A,Lomei J,Weström S,Shibuya M,Claesson-Welsh L,Gerwins P,Welsh M,Kreuger J,Phillipson M
Thu Oct 22 00:00:00 UTC 2015
Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin.
The Journal of experimental medicine
Frye M,Dierkes M,Küppers V,Vockel M,Tomm J,Zeuschner D,Rossaint J,Zarbock A,Koh GY,Peters K,Nottebaum AF,Vestweber D
Mon Dec 14 00:00:00 UTC 2015
Direct conversion of human amniotic cells into endothelial cells without transitioning through a pluripotent state.
Nature protocols
Ginsberg M,Schachterle W,Shido K,Rafii S
100-20 was used in Cell Culture to develop a method to directly convert human mid-gestation lineage-committed amniotic fluid-derived cells into vascular endothelial cells.
Tue Dec 01 00:00:00 UTC 2015
ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America
Morita R,Suzuki M,Kasahara H,Shimizu N,Shichita T,Sekiya T,Kimura A,Sasaki K,Yasukawa H,Yoshimura A
Tue Jan 06 00:00:00 UTC 2015
Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation.
Proceedings of the National Academy of Sciences of the United States of America
Jeon JS,Bersini S,Gilardi M,Dubini G,Charest JL,Moretti M,Kamm RD
Tue Jan 06 00:00:00 UTC 2015
Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance.
Aging cell
Zolla V,Nizamutdinova IT,Scharf B,Clement CC,Maejima D,Akl T,Nagai T,Luciani P,Leroux JC,Halin C,Stukes S,Tiwari S,Casadevall A,Jacobs WR,Entenberg D,Zawieja DC,Condeelis J,Fooksman DR,Gashev AA,Santambrogio L
Sat Aug 01 00:00:00 UTC 2015
ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation.
The Journal of cell biology
Tornavaca O,Chia M,Dufton N,Almagro LO,Conway DE,Randi AM,Schwartz MA,Matter K,Balda MS
Mon Mar 16 00:00:00 UTC 2015
Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes.
The Journal of cell biology
Grimsey NJ,Aguilar B,Smith TH,Le P,Soohoo AL,Puthenveedu MA,Nizet V,Trejo J
Mon Sep 28 00:00:00 UTC 2015
Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes.
Development (Cambridge, England)
Palpant NJ,Pabon L,Roberts M,Hadland B,Jones D,Jones C,Moon RT,Ruzzo WL,Bernstein I,Zheng Y,Murry CE
100-20 was used in In vitro experiments to conclude that activin/BMP gradients specify distinct mesodermal subpopulations that generate cell derivatives with unique angiogenic, hemogenic and cardiogenic properties that should be useful for understanding embryogenesis and developing therapeutics.
Tue Sep 15 00:00:00 UTC 2015
The alternative splicing factor Nova2 regulates vascular development and lumen formation.
Nature communications
Giampietro C,Deflorian G,Gallo S,Di Matteo A,Pradella D,Bonomi S,Belloni E,Nyqvist D,Quaranta V,Confalonieri S,Bertalot G,Orsenigo F,Pisati F,Ferrero E,Biamonti G,Fredrickx E,Taveggia C,Wyatt CD,Irimia M,Di Fiore PP,Blencowe BJ,Dejana E,Ghigna C
Thu Oct 08 00:00:00 UTC 2015
Enhanced therapeutic neovascularization by CD31-expressing cells and embryonic stem cell-derived endothelial cells engineered with chitosan hydrogel containing VEGF-releasing microtubes.
Biomaterials
Lee S,Valmikinathan CM,Byun J,Kim S,Lee G,Mokarram N,Pai SB,Um E,Bellamkonda RV,Yoon YS
100-20 was used in In vitro experiments to develop a novel chitosan-based hydrogel construct that encapsulates both CD31-expressing BM-mononuclear cells (BM-CD31(+) cells) and embryonic stem cell (ESC)-derived endothelial cells (ESC-ECs), and is loaded with VEGF-releasing microtubes.
Tue Sep 01 00:00:00 UTC 2015
Phosphatidylinositol 3-kinase class II α-isoform PI3K-C2α is required for transforming growth factor β-induced Smad signaling in endothelial cells.
The Journal of biological chemistry
Aki S,Yoshioka K,Okamoto Y,Takuwa N,Takuwa Y
Fri Mar 06 00:00:00 UTC 2015
Phosphatidylinositol 3-kinase class II α-isoform PI3K-C2α is required for transforming growth factor β-induced Smad signaling in endothelial cells.
The Journal of biological chemistry
Aki S,Yoshioka K,Okamoto Y,Takuwa N,Takuwa Y
Fri Mar 06 00:00:00 UTC 2015
A method to tune the shape of protein-encapsulated polymeric microspheres.
Scientific reports
de Alteriis R,Vecchione R,Attanasio C,De Gregorio M,Porzio M,Battista E,Netti PA
Thu Jul 30 00:00:00 UTC 2015
A method to tune the shape of protein-encapsulated polymeric microspheres.
Scientific reports
de Alteriis R,Vecchione R,Attanasio C,De Gregorio M,Porzio M,Battista E,Netti PA
Thu Jul 30 00:00:00 UTC 2015
Reinforcing endothelial junctions prevents microvessel permeability increase and tumor cell adhesion in microvessels in vivo.
Scientific reports
Fu BM,Yang J,Cai B,Fan J,Zhang L,Zeng M
Wed Oct 28 00:00:00 UTC 2015
Reinforcing endothelial junctions prevents microvessel permeability increase and tumor cell adhesion in microvessels in vivo.
Scientific reports
Fu BM,Yang J,Cai B,Fan J,Zhang L,Zeng M
Wed Oct 28 00:00:00 UTC 2015
Neurons limit angiogenesis by titrating VEGF in retina.
Cell
Okabe K,Kobayashi S,Yamada T,Kurihara T,Tai-Nagara I,Miyamoto T,Mukouyama YS,Sato TN,Suda T,Ema M,Kubota Y
Thu Oct 23 00:00:00 UTC 2014
Sensitizing protective tumor microenvironments to antibody-mediated therapy.
Cell
Pallasch CP,Leskov I,Braun CJ,Vorholt D,Drake A,Soto-Feliciano YM,Bent EH,Schwamb J,Iliopoulou B,Kutsch N,van Rooijen N,Frenzel LP,Wendtner CM,Heukamp L,Kreuzer KA,Hallek M,Chen J,Hemann MT
Thu Jan 30 00:00:00 UTC 2014
Manipulation of a VEGF-Notch signaling circuit drives formation of functional vascular endothelial progenitors from human pluripotent stem cells.
Cell research
Sahara M,Hansson EM,Wernet O,Lui KO,Später D,Chien KR
Tue Jul 01 00:00:00 UTC 2014
Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression.
Immunity
Stephen TL,Rutkowski MR,Allegrezza MJ,Perales-Puchalt A,Tesone AJ,Svoronos N,Nguyen JM,Sarmin F,Borowsky ME,Tchou J,Conejo-Garcia JR
Thu Sep 18 00:00:00 UTC 2014
Neuropilin-1 mediates myeloid cell chemoattraction and influences retinal neuroimmune crosstalk.
The Journal of clinical investigation
Dejda A,Mawambo G,Cerani A,Miloudi K,Shao Z,Daudelin JF,Boulet S,Oubaha M,Beaudoin F,Akla N,Henriques S,Menard C,Stahl A,Delisle JS,Rezende FA,Labrecque N,Sapieha P
Sat Nov 01 00:00:00 UTC 2014
Protein kinase LKB1 promotes RAB7-mediated neuropilin-1 degradation to inhibit angiogenesis.
The Journal of clinical investigation
Okon IS,Coughlan KA,Zhang C,Moriasi C,Ding Y,Song P,Zhang W,Li G,Zou MH
Wed Oct 01 00:00:00 UTC 2014
Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature.
The Journal of clinical investigation
Shen J,Frye M,Lee BL,Reinardy JL,McClung JM,Ding K,Kojima M,Xia H,Seidel C,Lima e Silva R,Dong A,Hackett SF,Wang J,Howard BW,Vestweber D,Kontos CD,Peters KG,Campochiaro PA
Wed Oct 01 00:00:00 UTC 2014
VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling.
Proceedings of the National Academy of Sciences of the United States of America
Favia A,Desideri M,Gambara G,D'Alessio A,Ruas M,Esposito B,Del Bufalo D,Parrington J,Ziparo E,Palombi F,Galione A,Filippini A
Tue Nov 04 00:00:00 UTC 2014
Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy.
British journal of cancer
Tazzari M,Negri T,Rini F,Vergani B,Huber V,Villa A,Dagrada P,Colombo C,Fiore M,Gronchi A,Stacchiotti S,Casali PG,Pilotti S,Rivoltini L,Castelli C
Tue Sep 23 00:00:00 UTC 2014
Suprabasin as a novel tumor endothelial cell marker.
Cancer science
Alam MT,Nagao-Kitamoto H,Ohga N,Akiyama K,Maishi N,Kawamoto T,Shinohara N,Taketomi A,Shindoh M,Hida Y,Hida K
Mon Dec 01 00:00:00 UTC 2014
TET2 deficiency inhibits mesoderm and hematopoietic differentiation in human embryonic stem cells.
Stem cells (Dayton, Ohio)
Langlois T,da Costa Reis Monte-Mor B,Lenglet G,Droin N,Marty C,Le Couédic JP,Almire C,Auger N,Mercher T,Delhommeau F,Christensen J,Helin K,Debili N,Fuks F,Bernard OA,Solary E,Vainchenker W,Plo I
Fri Aug 01 00:00:00 UTC 2014
Generation of iPSCs from genetically corrected Brca2 hypomorphic cells: implications in cell reprogramming and stem cell therapy.
Stem cells (Dayton, Ohio)
Navarro S,Moleiro V,Molina-Estevez FJ,Lozano ML,Chinchon R,Almarza E,Quintana-Bustamante O,Mostoslavsky G,Maetzig T,Galla M,Heinz N,Schiedlmeier B,Torres Y,Modlich U,Samper E,Río P,Segovia JC,Raya A,Güenechea G,Izpisua-Belmonte JC,Bueren JA
Sat Feb 01 00:00:00 UTC 2014
Drug-eluting beads loaded with antiangiogenic agents for chemoembolization: in vitro sunitinib loading and release and in vivo pharmacokinetics in an animal model.
Journal of vascular and interventional radiology : JVIR
Fuchs K,Bize PE,Dormond O,Denys A,Doelker E,Borchard G,Jordan O
100-20 was used in In vitro experiments to indicate the potential of sunitinib-eluting beads for use in embolization.
Sat Mar 01 00:00:00 UTC 2014
Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models.
Scientific reports
Chwalek K,Tsurkan MV,Freudenberg U,Werner C
Wed Mar 19 00:00:00 UTC 2014
YLT192, a novel, orally active bioavailable inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy in preclinical models.
Scientific reports
Xia Y,Song X,Li D,Ye T,Xu Y,Lin H,Meng N,Li G,Deng S,Zhang S,Liu L,Zhu Y,Zeng J,Lei Q,Pan Y,Wei Y,Zhao Y,Yu L
Tue Aug 12 00:00:00 UTC 2014
Neuron-derived neurotrophic factor functions as a novel modulator that enhances endothelial cell function and revascularization processes.
The Journal of biological chemistry
Ohashi K,Enomoto T,Joki Y,Shibata R,Ogura Y,Kataoka Y,Shimizu Y,Kambara T,Uemura Y,Yuasa D,Matsuo K,Hayakawa S,Hiramatsu-Ito M,Murohara T,Ouchi N
Fri May 16 00:00:00 UTC 2014
VEGF modulates synaptic activity in the developing spinal cord.
Developmental neurobiology
Guérit S,Allain AE,Léon C,Cazenave W,Ferrara N,Branchereau P,Bikfalvi A
100-20 was used in In vitro experiments to identify VEGF as a modulator of the neuronal activity during synapse formation and highlight a new ontogenic role for this angiogenic factor in the nervous system.
Sat Nov 01 00:00:00 UTC 2014
Testing an unusual in vivo vessel network model: a method to study angiogenesis in the colonial tunicate Botryllus schlosseri.
Scientific reports
Gasparini F,Caicci F,Rigon F,Zaniolo G,Manni L
Wed Sep 24 00:00:00 UTC 2014
Driving vascular endothelial cell fate of human multipotent Isl1+ heart progenitors with VEGF modified mRNA.
Cell research
Lui KO,Zangi L,Silva EA,Bu L,Sahara M,Li RA,Mooney DJ,Chien KR
Tue Oct 01 00:00:00 UTC 2013
Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity.
Blood
Singh N,Tiem M,Watkins R,Cho YK,Wang Y,Olsen T,Uehara H,Mamalis C,Luo L,Oakey Z,Ambati BK
Thu May 16 00:00:00 UTC 2013
Role of SOX17 in hematopoietic development from human embryonic stem cells.
Blood
Nakajima-Takagi Y,Osawa M,Oshima M,Takagi H,Miyagi S,Endoh M,Endo TA,Takayama N,Eto K,Toyoda T,Koseki H,Nakauchi H,Iwama A
Thu Jan 17 00:00:00 UTC 2013
Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
The Journal of experimental medicine
Soler A,Serra H,Pearce W,Angulo A,Guillermet-Guibert J,Friedman LS,Viñals F,Gerhardt H,Casanovas O,Graupera M,Vanhaesebroeck B
Mon Sep 23 00:00:00 UTC 2013
Neuroblastoma-derived TGF-β1 modulates the chemokine receptor repertoire of human resting NK cells.
Journal of immunology (Baltimore, Md. : 1950)
Castriconi R,Dondero A,Bellora F,Moretta L,Castellano A,Locatelli F,Corrias MV,Moretta A,Bottino C
Wed May 15 00:00:00 UTC 2013
Estradiol inhibits vascular endothelial cells pro-inflammatory activation induced by C-reactive protein.
Molecular and cellular biochemistry
Cossette É,Cloutier I,Tardif K,DonPierre G,Tanguay JF
Tue Jan 01 00:00:00 UTC 2013
Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.
PloS one
Pick M,Azzola L,Osborne E,Stanley EG,Elefanty AG
Thu Aug 08 00:00:00 UTC 2013
Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.
PloS one
Pick M,Azzola L,Osborne E,Stanley EG,Elefanty AG
Thu Aug 08 00:00:00 UTC 2013
Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR.
The Journal of biological chemistry
Kilari S,Remadevi I,Zhao B,Pan J,Miao R,Ramchandran R,North PE,You M,Rahimi N,Wilkinson GA
Fri Apr 12 00:00:00 UTC 2013
Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR.
The Journal of biological chemistry
Kilari S,Remadevi I,Zhao B,Pan J,Miao R,Ramchandran R,North PE,You M,Rahimi N,Wilkinson GA
Fri Apr 12 00:00:00 UTC 2013
Matrix metalloproteinase-1-mediated up-regulation of vascular endothelial growth factor-2 in endothelial cells.
The Journal of biological chemistry
Mazor R,Alsaigh T,Shaked H,Altshuler AE,Pocock ES,Kistler EB,Karin M,Schmid-Schönbein GW
Fri Jan 04 00:00:00 UTC 2013
The effect of Heparin-VEGF multilayer on the biocompatibility of decellularized aortic valve with platelet and endothelial progenitor cells.
PloS one
Ye X,Wang H,Zhou J,Li H,Liu J,Wang Z,Chen A,Zhao Q
Fri Sep 06 00:00:00 UTC 2013
Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors.
PloS one
Schwenke M,Knöfler M,Velicky P,Weimar CH,Kruse M,Samalecos A,Wolf A,Macklon NS,Bamberger AM,Gellersen B
Wed Jul 24 00:00:00 UTC 2013
MicroRNA-24 suppression of N-deacetylase/N-sulfotransferase-1 (NDST1) reduces endothelial cell responsiveness to vascular endothelial growth factor A (VEGFA).
The Journal of biological chemistry
Kasza Z,Fredlund Fuchs P,Tamm C,Eriksson AS,O'Callaghan P,Heindryckx F,Spillmann D,Larsson E,Le Jan S,Eriksson I,Gerwins P,Kjellén L,Kreuger J
Fri Sep 06 00:00:00 UTC 2013
A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer.
PloS one
Curtis VF,Wang H,Yang P,McLendon RE,Li X,Zhou QY,Wang XF
Fri Jul 26 00:00:00 UTC 2013
Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling.
Nature
Benedito R,Rocha SF,Woeste M,Zamykal M,Radtke F,Casanovas O,Duarte A,Pytowski B,Adams RH
Sun Mar 18 00:00:00 UTC 2012
Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling.
Nature
Benedito R,Rocha SF,Woeste M,Zamykal M,Radtke F,Casanovas O,Duarte A,Pytowski B,Adams RH
Sun Mar 18 00:00:00 UTC 2012
Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth.
Blood
Abéngozar MA,de Frutos S,Ferreiro S,Soriano J,Perez-Martinez M,Olmeda D,Marenchino M,Cañamero M,Ortega S,Megias D,Rodriguez A,Martínez-Torrecuadrada JL
Thu May 10 00:00:00 UTC 2012
Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth.
Blood
Abéngozar MA,de Frutos S,Ferreiro S,Soriano J,Perez-Martinez M,Olmeda D,Marenchino M,Cañamero M,Ortega S,Megias D,Rodriguez A,Martínez-Torrecuadrada JL
Thu May 10 00:00:00 UTC 2012
ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells.
Blood
Joo HJ,Choi DK,Lim JS,Park JS,Lee SH,Song S,Shin JH,Lim DS,Kim I,Hwang KC,Koh GY
Thu Sep 27 00:00:00 UTC 2012
APELIN promotes hematopoiesis from human embryonic stem cells.
Blood
Yu QC,Hirst CE,Costa M,Ng ES,Schiesser JV,Gertow K,Stanley EG,Elefanty AG
Thu Jun 28 00:00:00 UTC 2012
Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling.
The Journal of cell biology
Huveneers S,Oldenburg J,Spanjaard E,van der Krogt G,Grigoriev I,Akhmanova A,Rehmann H,de Rooij J
Mon Mar 05 00:00:00 UTC 2012
p120-catenin binding masks an endocytic signal conserved in classical cadherins.
The Journal of cell biology
Nanes BA,Chiasson-MacKenzie C,Lowery AM,Ishiyama N,Faundez V,Ikura M,Vincent PA,Kowalczyk AP
Mon Oct 15 00:00:00 UTC 2012
Inhibition of epidermal growth factor receptor tyrosine kinase ameliorates collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Swanson CD,Akama-Garren EH,Stein EA,Petralia JD,Ruiz PJ,Edalati A,Lindstrom TM,Robinson WH
Sun Apr 01 00:00:00 UTC 2012
Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
Gene therapy
Silk KM,Silk JD,Ichiryu N,Davies TJ,Nolan KF,Leishman AJ,Carpenter L,Watt SM,Cerundolo V,Fairchild PJ
Mon Oct 01 00:00:00 UTC 2012
Pattern of expression of vascular endothelial growth factor and its receptors in the ovine choroid plexus during long and short photoperiods.
Cell and tissue research
Szczepkowska A,Wąsowska B,Gilun PD,Lagaraine C,Robert V,Dufourny L,Thiéry JC,Skipor J
Mon Oct 01 00:00:00 UTC 2012
Transgenesis-mediated reproductive dysfunction and tumorigenesis: effects of immunological neutralization.
PloS one
Sachdeva R,Bhardwaj N,Huhtaniemi I,Aggrawal U,Jain SK,Zaidi R,Singh O,Pal R
Tue May 28 00:00:00 UTC 2013
The molecular balance between receptor tyrosine kinases Tie1 and Tie2 is dynamically controlled by VEGF and TNFα and regulates angiopoietin signalling.
PloS one
Singh H,Hansen TM,Patel N,Brindle NP
Mon May 14 00:00:00 UTC 2012
Dental pulp stem cells differentiation reveals new insights in Oct4A dynamics.
PloS one
Ferro F,Spelat R,D'Aurizio F,Puppato E,Pandolfi M,Beltrami AP,Cesselli D,Falini G,Beltrami CA,Curcio F
Wed Nov 28 00:00:00 UTC 2012
A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation.
Cell death & disease
Zhang YM,Dai BL,Zheng L,Zhan YZ,Zhang J,Smith WW,Wang XL,Chen YN,He LC
Thu Oct 11 00:00:00 UTC 2012
Reciprocal regulation of syndecan-2 and Notch signaling in vascular smooth muscle cells.
The Journal of biological chemistry
Zhao N,Liu H,Lilly B
Fri May 11 00:00:00 UTC 2012
Leukocyte inflammatory responses provoked by pneumococcal sialidase.
mBio
Chang YC,Uchiyama S,Varki A,Nizet V
Thu Apr 19 00:00:00 UTC 2012
Engineering of in vitro 3D capillary beds by self-directed angiogenic sprouting.
PloS one
Chan JM,Zervantonakis IK,Rimchala T,Polacheck WJ,Whisler J,Kamm RD
Tue Jun 11 00:00:00 UTC 2013
Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2.
PloS one
Dwyer J,Hebda JK,Le Guelte A,Galan-Moya EM,Smith SS,Azzi S,Bidere N,Gavard J
Wed Mar 06 00:00:00 UTC 2013
Extract of Pleurotus pulmonarius suppresses liver cancer development and progression through inhibition of VEGF-induced PI3K/AKT signaling pathway.
PloS one
Xu W,Huang JJ,Cheung PC
Fri Aug 03 00:00:00 UTC 2012
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell
Bock C,Kiskinis E,Verstappen G,Gu H,Boulting G,Smith ZD,Ziller M,Croft GF,Amoroso MW,Oakley DH,Gnirke A,Eggan K,Meissner A
Fri Feb 04 00:00:00 UTC 2011
NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.
Nature methods
Elliott DA,Braam SR,Koutsis K,Ng ES,Jenny R,Lagerqvist EL,Biben C,Hatzistavrou T,Hirst CE,Yu QC,Skelton RJ,Ward-van Oostwaard D,Lim SM,Khammy O,Li X,Hawes SM,Davis RP,Goulburn AL,Passier R,Prall OW,Haynes JM,Pouton CW,Kaye DM,Mummery CL,Elefanty AG,Stanley EG
Sun Oct 23 00:00:00 UTC 2011
Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice.
Cell research
Lu SJ,Li F,Yin H,Feng Q,Kimbrel EA,Hahm E,Thon JN,Wang W,Italiano JE,Cho J,Lanza R
Tue Mar 01 00:00:00 UTC 2011
Disruption of Src function potentiates Chk1-inhibitor-induced apoptosis in human multiple myeloma cells in vitro and in vivo.
Blood
Dai Y,Chen S,Shah R,Pei XY,Wang L,Almenara JA,Kramer LB,Dent P,Grant S
Thu Feb 10 00:00:00 UTC 2011
NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis.
Blood
Urso K,Alfranca A,Martínez-Martínez S,Escolano A,Ortega I,Rodríguez A,Redondo JM
Thu Jul 21 00:00:00 UTC 2011
Endothelial von Willebrand factor regulates angiogenesis.
Blood
Starke RD,Ferraro F,Paschalaki KE,Dryden NH,McKinnon TA,Sutton RE,Payne EM,Haskard DO,Hughes AD,Cutler DF,Laffan MA,Randi AM
Thu Jan 20 00:00:00 UTC 2011
Endothelial progenitor cell-dependent angiogenesis requires localization of the full-length form of uPAR in caveolae.
Blood
Margheri F,Chillà A,Laurenzana A,Serratì S,Mazzanti B,Saccardi R,Santosuosso M,Danza G,Sturli N,Rosati F,Magnelli L,Papucci L,Calorini L,Bianchini F,Del Rosso M,Fibbi G
Thu Sep 29 00:00:00 UTC 2011
Monocytic cells derived from human embryonic stem cells and fetal liver share common differentiation pathways and homeostatic functions.
Blood
Klimchenko O,Di Stefano A,Geoerger B,Hamidi S,Opolon P,Robert T,Routhier M,El-Benna J,Delezoide AL,Boukour S,Lescure B,Solary E,Vainchenker W,Norol F
Thu Mar 17 00:00:00 UTC 2011
Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo.
The Journal of experimental medicine
Broermann A,Winderlich M,Block H,Frye M,Rossaint J,Zarbock A,Cagna G,Linnepe R,Schulte D,Nottebaum AF,Vestweber D
Mon Nov 21 00:00:00 UTC 2011
E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models.
Cancer research
Bello E,Colella G,Scarlato V,Oliva P,Berndt A,Valbusa G,Serra SC,D'Incalci M,Cavalletti E,Giavazzi R,Damia G,Camboni G
Tue Feb 15 00:00:00 UTC 2011
E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models.
Cancer research
Bello E,Colella G,Scarlato V,Oliva P,Berndt A,Valbusa G,Serra SC,D'Incalci M,Cavalletti E,Giavazzi R,Damia G,Camboni G
Tue Feb 15 00:00:00 UTC 2011
Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair.
Proceedings of the National Academy of Sciences of the United States of America
Webber MJ,Tongers J,Newcomb CJ,Marquardt KT,Bauersachs J,Losordo DW,Stupp SI
Tue Aug 16 00:00:00 UTC 2011
Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair.
Proceedings of the National Academy of Sciences of the United States of America
Webber MJ,Tongers J,Newcomb CJ,Marquardt KT,Bauersachs J,Losordo DW,Stupp SI
Tue Aug 16 00:00:00 UTC 2011
High efficient isolation and systematic identification of human adipose-derived mesenchymal stem cells.
Journal of biomedical science
Yang XF,He X,He J,Zhang LH,Su XJ,Dong ZY,Xu YJ,Li Y,Li YL
Fri Aug 19 00:00:00 UTC 2011
Decrease in VEGF expression induces intussusceptive vascular pruning.
Arteriosclerosis, thrombosis, and vascular biology
Hlushchuk R,Ehrbar M,Reichmuth P,Heinimann N,Styp-Rekowska B,Escher R,Baum O,Lienemann P,Makanya A,Keshet E,Djonov V
Thu Dec 01 00:00:00 UTC 2011
Fibroblast growth factor 2 regulates endothelial cell sensitivity to sunitinib.
Oncogene
Welti JC,Gourlaouen M,Powles T,Kudahetti SC,Wilson P,Berney DM,Reynolds AR
Thu Mar 10 00:00:00 UTC 2011
Vascular endothelial growth factor stimulates endothelial colony forming cells proliferation and tubulogenesis by inducing oscillations in intracellular Ca2+ concentration.
Stem cells (Dayton, Ohio)
Dragoni S,Laforenza U,Bonetti E,Lodola F,Bottino C,Berra-Romani R,Carlo Bongio G,Cinelli MP,Guerra G,Pedrazzoli P,Rosti V,Tanzi F,Moccia F
Tue Nov 01 00:00:00 UTC 2011
Dissection of the biphasic nature of hypoxia-induced motogenic action in bone marrow-derived human mesenchymal stem cells.
Stem cells (Dayton, Ohio)
Busletta C,Novo E,Valfrè Di Bonzo L,Povero D,Paternostro C,Ievolella M,Mareschi K,Ferrero I,Cannito S,Compagnone A,Bandino A,Colombatto S,Fagioli F,Parola M
Wed Jun 01 00:00:00 UTC 2011
Debrided skin as a source of autologous stem cells for wound repair.
Stem cells (Dayton, Ohio)
Natesan S,Wrice NL,Baer DG,Christy RJ
Mon Aug 01 00:00:00 UTC 2011
Common lymphatic endothelial and vascular endothelial receptor-1 mediates the transmigration of regulatory T cells across human hepatic sinusoidal endothelium.
Journal of immunology (Baltimore, Md. : 1950)
Shetty S,Weston CJ,Oo YH,Westerlund N,Stamataki Z,Youster J,Hubscher SG,Salmi M,Jalkanen S,Lalor PF,Adams DH
Fri Apr 01 00:00:00 UTC 2011
Differential adhesion molecule expression during murine embryonic stem cell commitment to the hematopoietic and endothelial lineages.
PloS one
Stankovich BL,Aguayo E,Barragan F,Sharma A,Pallavicini MG
Thu Jan 05 00:00:00 UTC 2012
Direct sensing of endothelial oxidants by vascular endothelial growth factor receptor-2 and c-Src.
PloS one
Lee M,Choy WC,Abid MR
Thu May 03 00:00:00 UTC 2012
Calcium homeostasis in human induced pluripotent stem cell-derived cardiomyocytes.
Stem cell reviews and reports
Lee YK,Ng KM,Lai WH,Chan YC,Lau YM,Lian Q,Tse HF,Siu CW
Tue Nov 01 00:00:00 UTC 2011
Error-prone nonhomologous end joining repair operates in human pluripotent stem cells during late G2.
Aging
Bogomazova AN,Lagarkova MA,Tskhovrebova LV,Shutova MV,Kiselev SL
Wed Jun 01 00:00:00 UTC 2011
Endogenous expression of matriptase in neural progenitor cells promotes cell migration and neuron differentiation.
The Journal of biological chemistry
Fang JD,Chou HC,Tung HH,Huang PY,Lee SL
Fri Feb 18 00:00:00 UTC 2011
Entamoeba lysyl-tRNA synthetase contains a cytokine-like domain with chemokine activity towards human endothelial cells.
PLoS neglected tropical diseases
Castro de Moura M,Miro F,Han JM,Kim S,Celada A,Ribas de Pouplana L
Tue Nov 01 00:00:00 UTC 2011
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism.
PloS one
Garrido-Urbani S,Jemelin S,Deffert C,Carnesecchi S,Basset O,Szyndralewiez C,Heitz F,Page P,Montet X,Michalik L,Arbiser J,Rüegg C,Krause KH,Imhof BA
Mon Feb 07 00:00:00 UTC 2011
Physical passaging of embryoid bodies generated from human pluripotent stem cells.
PloS one
Son MY,Kim HJ,Kim MJ,Cho YS
Tue May 03 00:00:00 UTC 2011
Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma.
PloS one
Jham BC,Ma T,Hu J,Chaisuparat R,Friedman ER,Pandolfi PP,Schneider A,Sodhi A,Montaner S
Fri Apr 29 00:00:00 UTC 2011
Targeted decorin gene therapy delivered with adeno-associated virus effectively retards corneal neovascularization in vivo.
PloS one
Mohan RR,Tovey JC,Sharma A,Schultz GS,Cowden JW,Tandon A
Tue Feb 28 00:00:00 UTC 2012
SU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration.
Molecular vision
Thill M,Berna MJ,Kunst F,Wege H,Strunnikova NV,Gordiyenko N,Grierson R,Richard G,Csaky KG
Mon Jan 10 00:00:00 UTC 2011
Efficacious and safe tissue-selective controlled gene therapy approaches for the cornea.
PloS one
Mohan RR,Sinha S,Tandon A,Gupta R,Tovey JC,Sharma A
Tue Apr 12 00:00:00 UTC 2011
Protocadherin-12 cleavage is a regulated process mediated by ADAM10 protein: evidence of shedding up-regulation in pre-eclampsia.
The Journal of biological chemistry
Bouillot S,Tillet E,Carmona G,Prandini MH,Gauchez AS,Hoffmann P,Alfaidy N,Cand F,Huber P
Fri Apr 29 00:00:00 UTC 2011
Regulation of tumor angiogenesis by EZH2.
Cancer cell
Lu C,Han HD,Mangala LS,Ali-Fehmi R,Newton CS,Ozbun L,Armaiz-Pena GN,Hu W,Stone RL,Munkarah A,Ravoori MK,Shahzad MM,Lee JW,Mora E,Langley RR,Carroll AR,Matsuo K,Spannuth WA,Schmandt R,Jennings NB,Goodman BW,Jaffe RB,Nick AM,Kim HS,Guven EO,Chen YH,Li LY,Hsu MC,Coleman RL,Calin GA,Denkbas EB,Lim JY,Lee JS,Kundra V,Birrer MJ,Hung MC,Lopez-Berestein G,Sood AK
Mon Aug 09 00:00:00 UTC 2010
VEGF/VEGFR2 interaction down-regulates matrix metalloproteinase-9 via STAT1 activation and inhibits B chronic lymphocytic leukemia cell migration.
Blood
Ugarte-Berzal E,Redondo-Muñoz J,Eroles P,Del Cerro MH,García-Marco JA,Terol MJ,García-Pardo A
Thu Jan 28 00:00:00 UTC 2010
Angiogenic factor signaling regulates centrosome duplication in endothelial cells of developing blood vessels.
Blood
Taylor SM,Nevis KR,Park HL,Rogers GC,Rogers SL,Cook JG,Bautch VL
Thu Oct 21 00:00:00 UTC 2010
Toll-like receptor 2/6 stimulation promotes angiogenesis via GM-CSF as a potential strategy for immune defense and tissue regeneration.
Blood
Grote K,Schuett H,Salguero G,Grothusen C,Jagielska J,Drexler H,Mühlradt PF,Schieffer B
Thu Mar 25 00:00:00 UTC 2010
Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity.
Blood
Verma A,Bhattacharya R,Remadevi I,Li K,Pramanik K,Samant GV,Horswill M,Chun CZ,Zhao B,Wang E,Miao RQ,Mukhopadhyay D,Ramchandran R,Wilkinson GA
Thu Jun 03 00:00:00 UTC 2010
Retinoic acid enhances the generation of hematopoietic progenitors from human embryonic stem cell-derived hemato-vascular precursors.
Blood
Yu C,Liu Y,Miao Z,Yin M,Lu W,Lv Y,Ding M,Deng H
Thu Dec 02 00:00:00 UTC 2010
Anti-angiogenic effects of resveratrol mediated by decreased VEGF and increased TSP1 expression in melanoma-endothelial cell co-culture.
Angiogenesis
Trapp V,Parmakhtiar B,Papazian V,Willmott L,Fruehauf JP
Wed Dec 01 00:00:00 UTC 2010
Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth.
Oncogene
Cantelmo AR,Cammarota R,Noonan DM,Focaccetti C,Comoglio PM,Prat M,Albini A
Thu Sep 23 00:00:00 UTC 2010
The retinoid signaling pathway inhibits hematopoiesis and uncouples from the Hox genes during hematopoietic development.
Stem cells (Dayton, Ohio)
Szatmari I,Iacovino M,Kyba M
Wed Sep 01 00:00:00 UTC 2010
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Journal of immunology (Baltimore, Md. : 1950)
Oo YH,Weston CJ,Lalor PF,Curbishley SM,Withers DR,Reynolds GM,Shetty S,Harki J,Shaw JC,Eksteen B,Hubscher SG,Walker LS,Adams DH
Mon Mar 15 00:00:00 UTC 2010
Osteoblasts are a major source of inflammatory cytokines in the tumor microenvironment of bone metastatic breast cancer.
Journal of cellular biochemistry
Bussard KM,Venzon DJ,Mastro AM
Wed Dec 01 00:00:00 UTC 2010
VEGF stimulates RCAN1.4 expression in endothelial cells via a pathway requiring Ca2+/calcineurin and protein kinase C-delta.
PloS one
Holmes K,Chapman E,See V,Cross MJ
Tue Jul 06 00:00:00 UTC 2010
Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.
PloS one
Nishiguchi KM,Kataoka K,Kachi S,Komeima K,Terasaki H
Wed Oct 20 00:00:00 UTC 2010
Generic approach for the generation of stable humanized single-chain Fv fragments from rabbit monoclonal antibodies.
The Journal of biological chemistry
Borras L,Gunde T,Tietz J,Bauer U,Hulmann-Cottier V,Grimshaw JP,Urech DM
Fri Mar 19 00:00:00 UTC 2010
Dynamic interaction networks in a hierarchically organized tissue.
Molecular systems biology
Kirouac DC,Ito C,Csaszar E,Roch A,Yu M,Sykes EA,Bader GD,Zandstra PW
Tue Oct 05 00:00:00 UTC 2010
Localization of angiotensin converting enzyme in rabbit cornea and its role in controlling corneal angiogenesis in vivo.
Molecular vision
Sharma A,Bettis DI,Cowden JW,Mohan RR
Fri Apr 23 00:00:00 UTC 2010
Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells.
Blood
McKinney-Freeman SL,Naveiras O,Yates F,Loewer S,Philitas M,Curran M,Park PJ,Daley GQ
Thu Jul 09 00:00:00 UTC 2009
Heme oxygenase-1 expression enhances vascular endothelial resistance to complement-mediated injury through induction of decay-accelerating factor: a role for increased bilirubin and ferritin.
Blood
Kinderlerer AR,Pombo Gregoire I,Hamdulay SS,Ali F,Steinberg R,Silva G,Ali N,Wang B,Haskard DO,Soares MP,Mason JC
Thu Feb 12 00:00:00 UTC 2009
The influence of the sequential delivery of angiogenic factors from affinity-binding alginate scaffolds on vascularization.
Biomaterials
Freeman I,Cohen S
Wed Apr 01 00:00:00 UTC 2009
Erlotinib and bevacizumab have synergistic activity against melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Schicher N,Paulitschke V,Swoboda A,Kunstfeld R,Loewe R,Pilarski P,Pehamberger H,Hoeller C
Fri May 15 00:00:00 UTC 2009
Impairment of plasmacytoid dendritic cells for IFN production by the ligand for immunoglobulin-like transcript 7 expressed on human cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Tsukamoto N,Okada S,Onami Y,Sasaki Y,Umezawa K,Kawakami Y
Tue Sep 15 00:00:00 UTC 2009
Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma.
Cancer research
Hu J,Dong A,Fernandez-Ruiz V,Shan J,Kawa M,Martínez-Ansó E,Prieto J,Qian C
Tue Sep 01 00:00:00 UTC 2009
Sprouty4 negatively regulates protein kinase C activation by inhibiting phosphatidylinositol 4,5-biphosphate hydrolysis.
Oncogene
Ayada T,Taniguchi K,Okamoto F,Kato R,Komune S,Takaesu G,Yoshimura A
Thu Feb 26 00:00:00 UTC 2009
TGFbeta1 antagonistic peptides inhibit TGFbeta1-dependent angiogenesis.
Biochemical pharmacology
Serratì S,Margheri F,Pucci M,Cantelmo AR,Cammarota R,Dotor J,Borràs-Cuesta F,Fibbi G,Albini A,Del Rosso M
100-20 was used in In vitro experiments to show that TGFbeta up-regulates expression not only of plasminogen activator inhibitor type-1 (PAI-1), but also of the urokinase-type plasminogen activator receptor (uPAR), whose inhibition by specific antibodies blunted the TGFbeta angiogenic response in vitro.
Sun Mar 01 00:00:00 UTC 2009
A feeder-free and efficient production of functional neutrophils from human embryonic stem cells.
Stem cells (Dayton, Ohio)
Saeki K,Saeki K,Nakahara M,Matsuyama S,Nakamura N,Yogiashi Y,Yoneda A,Koyanagi M,Kondo Y,Yuo A
Thu Jan 01 00:00:00 UTC 2009
Hematopoietic and endothelial differentiation of human induced pluripotent stem cells.
Stem cells (Dayton, Ohio)
Choi KD,Yu J,Smuga-Otto K,Salvagiotto G,Rehrauer W,Vodyanik M,Thomson J,Slukvin I
Sun Mar 01 00:00:00 UTC 2009
Differential gene expression in a coculture model of angiogenesis reveals modulation of select pathways and a role for Notch signaling.
Physiological genomics
Lilly B,Kennard S
Thu Jan 08 00:00:00 UTC 2009
Contribution of rat endothelial progenitor cells on three-dimensional network formation in vitro.
Tissue engineering. Part A
Koga M,Sudo R,Abe Y,Yamamoto K,Ando J,Ikeda M,Tanishita K
Tue Sep 01 00:00:00 UTC 2009
Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model.
Tissue engineering. Part A
Young S,Patel ZS,Kretlow JD,Murphy MB,Mountziaris PM,Baggett LS,Ueda H,Tabata Y,Jansen JA,Wong M,Mikos AG
Tue Sep 01 00:00:00 UTC 2009
Evidence for in vivo growth potential and vascular remodeling of tissue-engineered artery.
Tissue engineering. Part A
Cho SW,Kim IK,Kang JM,Song KW,Kim HS,Park CH,Yoo KJ,Kim BS
Wed Apr 01 00:00:00 UTC 2009
Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1.
Genome medicine
Larsson E,Fredlund Fuchs P,Heldin J,Barkefors I,Bondjers C,Genové G,Arrondel C,Gerwins P,Kurschat C,Schermer B,Benzing T,Harvey SJ,Kreuger J,Lindahl P
Mon Nov 16 00:00:00 UTC 2009
Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis.
The Journal of biological chemistry
Robinson SD,Reynolds LE,Kostourou V,Reynolds AR,da Silva RG,Tavora B,Baker M,Marshall JF,Hodivala-Dilke KM
Fri Dec 04 00:00:00 UTC 2009
Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway.
The Journal of biological chemistry
Ardi VC,Van den Steen PE,Opdenakker G,Schweighofer B,Deryugina EI,Quigley JP
Fri Sep 18 00:00:00 UTC 2009
Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway.
The Journal of biological chemistry
Ardi VC,Van den Steen PE,Opdenakker G,Schweighofer B,Deryugina EI,Quigley JP
Fri Sep 18 00:00:00 UTC 2009
Sox18 induces development of the lymphatic vasculature in mice.
Nature
François M,Caprini A,Hosking B,Orsenigo F,Wilhelm D,Browne C,Paavonen K,Karnezis T,Shayan R,Downes M,Davidson T,Tutt D,Cheah KS,Stacker SA,Muscat GE,Achen MG,Dejana E,Koopman P
Thu Dec 04 00:00:00 UTC 2008
Synergistic antitumor activity of ixabepilone (BMS-247550) plus bevacizumab in multiple in vivo tumor models.
Clinical cancer research : an official journal of the American Association for Cancer Research
Lee FY,Covello KL,Castaneda S,Hawken DR,Kan D,Lewin A,Wen ML,Ryseck RP,Fairchild CR,Fargnoli J,Kramer R
Mon Dec 15 00:00:00 UTC 2008
Transplantation of vascular cells derived from human embryonic stem cells contributes to vascular regeneration after stroke in mice.
Journal of translational medicine
Oyamada N,Itoh H,Sone M,Yamahara K,Miyashita K,Park K,Taura D,Inuzuka M,Sonoyama T,Tsujimoto H,Fukunaga Y,Tamura N,Nakao K
Tue Sep 30 00:00:00 UTC 2008
Transplantation of vascular cells derived from human embryonic stem cells contributes to vascular regeneration after stroke in mice.
Journal of translational medicine
Oyamada N,Itoh H,Sone M,Yamahara K,Miyashita K,Park K,Taura D,Inuzuka M,Sonoyama T,Tsujimoto H,Fukunaga Y,Tamura N,Nakao K
Tue Sep 30 00:00:00 UTC 2008
Extracellular RNA mediates endothelial-cell permeability via vascular endothelial growth factor.
Blood
Fischer S,Gerriets T,Wessels C,Walberer M,Kostin S,Stolz E,Zheleva K,Hocke A,Hippenstiel S,Preissner KT
Mon Oct 01 00:00:00 UTC 2007
Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor.
The Journal of experimental medicine
Alexander-Brett JM,Fremont DH
Mon Dec 24 00:00:00 UTC 2007
Sustained release of bioactive therapeutic proteins from a biodegradable elastomeric device.
Journal of controlled release : official journal of the Controlled Release Society
Gu F,Neufeld R,Amsden B
Mon Jan 22 00:00:00 UTC 2007
The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.
Stem cells (Dayton, Ohio)
Ponte AL,Marais E,Gallay N,Langonné A,Delorme B,Hérault O,Charbord P,Domenech J
Sun Jul 01 00:00:00 UTC 2007
Inhibition of growth of experimental human endometrial cancer by an antagonist of growth hormone-releasing hormone.
The Journal of clinical endocrinology and metabolism
Engel JB,Keller G,Schally AV,Toller GL,Groot K,Havt A,Armatis P,Zarandi M,Varga JL,Halmos G
Wed Jun 01 00:00:00 UTC 2005
Enhanced protein profiling arrays with ELISA-based amplification for high-throughput molecular changes of tumor patients' plasma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Huang R,Lin Y,Shi Q,Flowers L,Ramachandran S,Horowitz IR,Parthasarathy S,Huang RP
Thu Jan 15 00:00:00 UTC 2004
Bombesin antagonists inhibit proangiogenic factors in human experimental breast cancers.
British journal of cancer
Bajo AM,Schally AV,Groot K,Szepeshazi K
Mon Jan 12 00:00:00 UTC 2004
Direct regulation of prostate blood flow by vascular endothelial growth factor and its participation in the androgenic regulation of prostate blood flow in vivo.
Endocrinology
Shibata Y,Kashiwagi B,Arai S,Fukabori Y,Suzuki K,Honma S,Yamanaka H
Fri Oct 01 00:00:00 UTC 2004
Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites.
The Journal of biological chemistry
Dixelius J,Makinen T,Wirzenius M,Karkkainen MJ,Wernstedt C,Alitalo K,Claesson-Welsh L
100-20 was used in Cell Culture to study five tyrosyl phosphorylation sites in the vascular endothelial growth factor receptor-3 (VEGFR-3) carboxyl-terminal tail and suggest that it provides important regulatory tyrosine phosphorylation sites with potential signal transduction capacity and that these sites are differentially used in ligand-induced homo- and heterodimeric receptor complexes.
Fri Oct 17 00:00:00 UTC 2003
Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1.
Blood
Salvucci O,Yao L,Villalba S,Sajewicz A,Pittaluga S,Tosato G
Mon Apr 15 00:00:00 UTC 2002
Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells.
Blood
Burger PE,Coetzee S,McKeehan WL,Kan M,Cook P,Fan Y,Suda T,Hebbel RP,Novitzky N,Muller WA,Wilson EL
Fri Nov 15 00:00:00 UTC 2002
Embryonic stem cell-derived embryoid bodies development in collagen gels recapitulates sprouting angiogenesis.
Laboratory investigation; a journal of technical methods and pathology
Feraud O,Cao Y,Vittet D
Sat Dec 01 00:00:00 UTC 2001
Embryonic stem cell-derived embryoid bodies development in collagen gels recapitulates sprouting angiogenesis.
Laboratory investigation; a journal of technical methods and pathology
Feraud O,Cao Y,Vittet D
Sat Dec 01 00:00:00 UTC 2001
In vitro differentiation of endothelial cells from AC133-positive progenitor cells.
Blood
Gehling UM,Ergün S,Schumacher U,Wagener C,Pantel K,Otte M,Schuch G,Schafhausen P,Mende T,Kilic N,Kluge K,Schäfer B,Hossfeld DK,Fiedler W
Mon May 15 00:00:00 UTC 2000
