The heterobifunctional, crossslinker succinimidyl 3-(2-pyridyldithio)propionate (SPDP) enables one to covalently link two target groups. The succinimidyl ester chemically reacts with primary amines and after mild reduction of the dithiol, it can react form a disulfide with other thiols. Crosslinking reagents are useful for probing the spatial relationships and interactions within and between biomolecules.
For Research Use Only. Not for use in diagnostic procedures.
Especificações
Chemical Reactivity
Amine-Sulfhydryl
Cleavable
By Thiols
Description
SPDP
Molecular Weight (g/mol)
312.36
PEGylated
No
Spacer Arm Length
6.8 Å
Cell Permeability
Yes
Labeling Method
Chemical Labeling
Crosslinker Type
Heterobifunctional
Reactive Moiety
NHS Ester, Pyridyldisulfide
Spacer
Short (<10 Å)
Form
Solid
Quantity
100 mg
Solubility
DMF, DMSO
Format
Standard
Water Soluble
No
Product Type
Crosslinker
Conteúdo e armazenamento
Upon receipt store at -20°C protected from light.
Figuras
Documentos e downloads
Certificados
Pesquisar por número de lote ou número de lote parcial