TheraPure™ GMP Pyrophosphatase, inorganic, 1 U/μL
TheraPure™ GMP Pyrophosphatase, inorganic, 1 U/μL
TheraPure™ GMP Pyrophosphatase, inorganic, 1 U/μL
TheraPure™ GMP Pyrophosphatase, inorganic, 1 U/μL
Thermo Scientific™

TheraPure™ GMP Pyrophosphatase, inorganic, 1 U/μL

Thermo Scientific TheraPure GMP* Pyrophosphatase, inorganic, is manufactured to ICH Q7 GMP principles and supported by a comprehensive documentation package.Weitere Informationen
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KatalognummerMenge
EF022SKAFB0015 kU
EF022SKAFB00220 kU
EF022SKAFB0038 kU
Katalognummer EF022SKAFB001
Preis (EUR)
-
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Menge:
5 kU
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Thermo Scientific TheraPure GMP* Pyrophosphatase, inorganic, is manufactured to ICH Q7 GMP principles and supported by a comprehensive documentation package. It is specifically designed for the development and manufacturing of mRNA therapeutics and vaccines. Also known as inorganic diphoshatase or PPase, it catalyzes the hydrolysis of inorganic pyrophosphate (PPi) generated by in vitro transcription reactions into two orthophosphates (Pi):
P2O74- (PPi) + H2O → 2 HPO42- (2 Pi)

Designed for process development and manufacturing
TheraPure GMP Pyrophosphatase, Inorganic, helps accelerate mRNA vaccine and therapeutics production from preclinical development to commercialization by providing:
Quality—meet critical product quality needs to help accelerate therapeutic development and manufacturing
Minimal risk—help reduce risks in developing therapeutics by utilizing proven products
Technical partnership—partner with expert product and technical support
Secure and consistent supply—count on a secure and stable supply of product at a global scale

Comprehensive quality system
TheraPure GMP Pyrophosphatase is supported by a extensive quality system and documentation including:
• Manufactured to relevant ICH Q7 GMP guidelines
• Animal-origin free (AOF) manufacturing processes, materials, and facilities
• Validated manufacturing processes and analytical test methods
• Comprehensive impurity profiles
• Verified compendial assays where applicable
• Product stability data
• Tested by analytical methods following ICH Q2 guidelines whenever possible
• Drug master file (DMF)

Enzyme activity
One unit of enzyme catalyzes the hydrolysis of 1 μmol of inorganic pyrophosphate in 1 min at 25°C.

For additional TheraPure GMP products or customization, please visit www.thermofisher.com/therapure.

*TheraPure GMP refers to the quality level of the raw, ancillary, or starting materials to be used for further manufacturing. TheraPure GMP products are manufactured in facilities with ISO 9001–certified quality management systems that operate in accordance with relevant good manufacturing practice (GMP) principles, as outlined in ICH Q7 or equivalent guidance documents or standards.

For Research Use or Further Manufacturing. Not for diagnostic use or direct administration into humans or animals.
Specifications
Biologische AktivitätPyrophosphatase
FarbeTransparent
ExpressionssystemE. coli
Zur Verwendung mit (Anwendung)In vitro transcription
Masse32 kDa
ProdukttypPyrophosphatase
Reinheit≥95%
Menge5 kU
QuelleSaccharomyces cerevisiae
Lagerungspuffer10 mM Tris-HCl pH 7.5, 0.1 mM EDTA, 5 mM DTT, 50% glycerol
Konzentration1 U/μl
EnzymPyrophosphatase
FormFlüssig
ProduktlinieTheraPure™ GMP
pH7.1 to 7.9
Unit SizeEach
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