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Alendronate sodium trihydrate, 97%, Thermo Scientific Chemicals
Katalognummer: J61397.03
1 g, Each
Thermo Scientific Chemicals
Alendronate sodium trihydrate, 97%, Thermo Scientific Chemicals
Katalognummer: J61397.03
1 g, Each
Menge
Katalognummer: J61397.03
auch als J61397-03 bezeichnet
Preis (EUR)
44,46 Online-Preis
49,40
Each
Menge
-
Chemikalien-Kennzeichnungen
CAS
121268-17-5
IUPAC Name
sodium trihydrate hydrogen (4-amino-1-hydroxy-1-phosphonobutyl)phosphonate
Molecular Formula
C4H18NNaO10P2
InChI Key
DCSBSVSZJRSITC-UHFFFAOYNA-M
SMILES
O.O.O.[Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
Spezifikationen
DatenblattForm
Powder or crystals or crystalline powder
Identification (FTIR)
Conforms
Assay from Supplier's CofA
≥96.0%
Appearance (Color)
White to pale cream
Loss on Drying
14.0-19.0%
Beschreibung
Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.
Solubility
Soluble in water at 10mg/ml
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.
Solubility
Soluble in water at 10mg/ml
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
RUO – Research Use Only
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Sicherheit und Handhabung
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Label Elements
Signal Word
Warning
Hazard Statements
H302 - Harmful if swallowed
Precautionary Statements
P264 - Wash face, hands and any exposed skin thoroughly after handling
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P312 - Call a POISON CENTER or doctor if you feel unwell