Qtracker™ 705 Vascular Labels
Qtracker™ 705 Vascular Labels
Invitrogen™

Qtracker™ 705 Vascular Labels

Qtracker™ nicht zielgerichtete Quantenpunkte werden in die Schwanzvene von Mäusen injiziert, um die Gefäßstruktur mittels In-vivo-Bildgebungsverfahren für Kleintiere (SAIVI) zuWeitere Informationen
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KatalognummerMenge
Q21061MP200 μl
Katalognummer Q21061MP
Preis (EUR)
1.088,00
Each
-
Zum Warenkorb hinzufügen
Menge:
200 μl
Preis (EUR)
1.088,00
Each
Zum Warenkorb hinzufügen
Ask our AI about this Product
Qtracker™ nicht zielgerichtete Quantenpunkte werden in die Schwanzvene von Mäusen injiziert, um die Gefäßstruktur mittels In-vivo-Bildgebungsverfahren für Kleintiere (SAIVI) zu untersuchen. Diese Nanokristalle besitzen eine intensive Fluoreszenz mit rot verschobener Emission für eine erhöhte Gewebepenetration und verfügen über eine PEG-Oberflächenbeschichtung, die speziell zum Minimieren unspezifischer Wechselwirkungen sowie Verringern der Immunantwort durch Gewebe entwickelt wurde. Da die PEG-Oberflächenbeschichtung keine reaktiven Funktionsgruppen enthält, bleiben Qtracker™ nicht zielgerichtete Quantenpunkte länger im Umlauf und können mit einer Einzelinjektion bis zu 3 Stunden lang oder mit zusätzlichen Injektionen über längere Zeiträume abgebildet werden.

Benötigen Sie ein anderes Emissionsspektrum oder ein längeres Tracking? Hier finden Sie unsere übrigen Tracking-Produkte für Säugetier-Zellkulturen.

Hauptmerkmale:

Qtracker™ 705-Marker besitzt Anregungs-/Emissionslinien (Ex/Em) von (405-665/705) nm
Konzipiert für die In-vivo-Bildgebung
Wird über Schwanzveneninjektion eingebracht und ist bis zu 3 Stunden nach der Injektion abbildbar
Erhältlich in vier Farben—Emissionslinien 565 nm, 655 nm, 705 nm oder 800 nm

Weitere Informationen zu SAIVI und Anwendungsfälle für Qdot™ Nanokristalle.

Nur für Forschungszwecke. Nicht für therapeutische oder diagnostische Zwecke an Tieren und Menschen vorgesehen.
Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.
Specifications
Konzentration2 μM
FarbstofftypQdot Nanokristalle
ProduktlinieQTRACKER™, Qdot™
Menge200 μl
ReagenztypReagenzien für die Gefäßbildgebung
VersandbedingungRaumtemperatur, Raumtemperatur
VerfahrenIn-vivo-Bildgebung, In-vivo-Bildgebung
ProdukttypEtikett
Unit SizeEach
Inhalt und Lagerung
Enthält 200 μl Qtracker™ nicht zielgerichtete Quantenpunkte (2 μM Lösung in 50 mM Boratpuffer, pH 8,3). Bei 2 bis 6 °C lagern. Nicht einfrieren. Mindestens 6 Monate stabil.
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Fluoreszenzspektren

Fluorescence spectra

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Zertifikate

Chargen-Nr.Certificate TypeDateCatalog Number(s)
3184513Certificate of Analysis28. Mai 2025Q21061MP
2714509Certificate of Analysis16. Nov. 2023Q21061MP
2544403Certificate of Analysis20. Okt. 2022Q21061MP
2561625Certificate of Analysis27. Jan. 2022Q21061MP
2307879Certificate of Analysis05. Aug. 2021Q21061MP
5 Ergebnisse angezeigt, oben nach einem bestimmten Zertifikat suchen

Sicherheitsdatenblätter

Handbuch Molecular Probes®

Häufig gestellte Fragen (FAQ)

Qtracker cell labeling reagents are taken up by the cell through endocytosis and sequestered in endosomes. This gives the label a punctate or vesicular appearance. This is normal. There is nothing that can be done to make it appear uniform throughout the cytoplasm.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

The imaging time course varies with the nature of the injected agent. Vascular tracers are visible in the blood vessels immediately after injection and may be imaged for several hours. Conjugated whole IgG antibodies reach their targets within a few hours of injection and may be imaged for several days.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

The dye will be eliminated via the bladder. The bladder signal is detectable within ~3 minutes of IV injection of the dye and clearance with ~30 minutes.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

A recommended starting dosage is 25-50 µL of Qtracker reagent diluted to the desired injection volume with PBS or normal saline. Qtracker reagent should be diluted immediately prior to injection. DO NOT STORE DILUTED. You will need to determine the optimal dosage for your experimental models.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

This is not recommended. When these stains bind to DNA and RNA, they may affect the normal function of the nucleic acids, disrupting transcription, as well as replication. Other reagents, such as CellTracker dyes or Qtracker reagents are more optimized for tracking without disrupting normal activity. If a nuclear label is still desired, though, and the cells are mammalian and non-hematopoietic, CellLight nuclear reagents can transiently transfect cells to express GFP or RFP on a nuclear-expressing protein for up to several days without affecting function.

Find additional tips, troubleshooting help, and resources within our Cell Tracing and Tracking Support Center.

Zitierungen und Referenzen (17)

Zitierungen und Referenzen
Abstract
Noninvasive imaging of quantum dots in mice.
Authors:Ballou B, Lagerholm BC, Ernst LA, Bruchez MP, Waggoner AS
Journal:Bioconjug Chem
PubMed ID:14733586
'Quantum dots having four different surface coatings were tested for use in in vivo imaging. Localization was successfully monitored by fluorescence imaging of living animals, by necropsy, by frozen tissue sections for optical microscopy, and by electron microscopy, on scales ranging from centimeters to nanometers, using only quantum dots for ... More
In vivo imaging of quantum dots.
Authors:Texier I, Josser V,
Journal:Methods Mol Biol
PubMed ID:19488714
'Noninvasive whole-body near-infrared fluorescence imaging is now acknowledged as a powerful method for the molecular mapping of biological events in live small animals such as mouse models. With outstanding optical properties such as high fluorescence quantum yields and low photobleaching rates, quantum dots (QDs) are labels of choice in the ... More
Imaging takes a quantum leap.
Authors:Lidke DS, Arndt-Jovin DJ
Journal:Physiology (Bethesda)
PubMed ID:15546848
Semiconducting nanocrystals, or quantum dots (QDs), have emerged as a new tool in physiological imaging, combining high brilliance, photostability, broad excitation but very narrow emission spectra, and surface chemistry compatible with biomolecular conjugation. In this review, we demonstrate the power of QDs in diverse applications, including long-term in vivo fluorescence ... More
In vivo excitation of nanoparticles using luminescent bacteria.
Authors:Dragavon J, Blazquez S, Rekiki A, Samson C, Theodorou I, Rogers KL, Tournebize R, Shorte SL,
Journal:Proc Natl Acad Sci U S A
PubMed ID:22615349
The lux operon derived from Photorhabdus luminescens incorporated into bacterial genomes, elicits the production of biological chemiluminescence typically centered on 490 nm. The light-producing bacteria are widely used for in vivo bioluminescence imaging. However, in living samples, a common difficulty is the presence of blue-green absorbers such as hemoglobin. Here we ... More
Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization.
Authors:Park C, Hwang IY, Sinha RK, Kamenyeva O, Davis MD, Kehrl JH,
Journal:Blood
PubMed ID:22039261
B lymphocyte recirculation through lymph nodes (LNs) requires crossing endothelial barriers and chemoattractant-triggered cell migration. Here we show how LN anatomy and chemoattractant receptor signaling organize B lymphocyte LN trafficking. Blood-borne B cells predominately used CCR7 signaling to adhere to high endothelial venules (HEVs). New B cell emigrants slowly transited ... More
17 total citations

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