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Trifluoroacetic acid, HPLC Grade, 99.5+%, Thermo Scientific Chemicals
Catalog number: 044630.AP
500 mL, Each
Thermo Scientific Chemicals
Trifluoroacetic acid, HPLC Grade, 99.5+%, Thermo Scientific Chemicals
Catalog number: 044630.AP
500 mL, Each
Quantity
Chemical Identifiers
CAS
76-05-1
IUPAC Name
trifluoroacetic acid
Molecular Formula
C2HF3O2
InChI Key
DTQVDTLACAAQTR-UHFFFAOYSA-N
SMILES
OC(=O)C(F)(F)F
Specifications
Specification SheetForm
Liquid
Optical Absorbance at
210 nm, 1.00 AU, max
Appearance (Color)
Clear colorless
Assay (Aqueous acid-base Titration)
≥99.5%
Optical Absorbance at
230 nm, 0.15 AU, max
Description
The combination of properties like solubility in most of the solvents, volatility, catalytic property and strong acidity with non-oxidizing nature makes it a widely used reagent in an organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and ceramic compounds. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. It finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute Inhalation Toxicity - Vapors
Category 4
Skin Corrosion/Irritation
Category 1
Serious Eye Damage/Eye Irritation
Category 1
Chronic aquatic toxicity
Category 3
Label Elements
Signal Word
Danger
Hazard Statements
H314 - Causes severe skin burns and eye damage
H332 - Harmful if inhaled
H412 - Harmful to aquatic life with long lasting effects
EU Specific Hazard Statements
EUH071 - Corrosive to the respiratory tract
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician