Separate proteins and their variants using Thermo Scientific™ ProPac™ SCX-10 LC Columns, which provide exceptionally high resolution. Based on stationary phases composed of 10μm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions. The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

• Nonporous core particle results in high-efficiency peaks and high-resolution separations of protein variants
• Hydrophilic layer prevents unwanted secondary interactions
• Grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity
• Useful for characterization of related protein variants