Ribavirin, 98%, Thermo Scientific Chemicals
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Ribavirin, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Ribavirin, 98%, Thermo Scientific Chemicals

Ribavirin, CAS# 36791-04-5, is an antiviral agent and a guanosine analog, which stops viral RNA synthesis and mRNA capping.
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25 g
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5 g
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Catalog number 460480250
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Quantity:
25 g
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Chemical Identifiers
CAS36791-04-5
IUPAC Name1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
Molecular FormulaC8H12N4O5
InChI KeyIWUCXVSUMQZMFG-AFCXAGJDSA-N
SMILESNC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
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SpecificationsSpecification SheetSpecification Sheet
HPLC>=97.5 %
Specific optical rotation-33° to -37° (20°C, 589 nm) (1 % in water)
Residue after ign. (sulfated)=<0.25 %
Appearance (Color)White to off-white
Appearance (Form)Powder
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• Ribavirin is a broad-spectrum antiviral nucleoside analog
• It inhibits viral genome synthesis
Applications
• Ribavirin is an antiviral compound
• Its metabolite, ribavirin 5'-phosphate, inhibits inosine monophosphate dehydrogenase (IMP), which is involved in GTP biosynthesis
RUO – Research Use Only

General References:

  1. Keppeke, G.D.; et al. IMP/GTP balance modulates cytoophidium assembly and IMPDH activity. Cell Div. 2018, 15,13:5.
  2. Li, W.; Shen, F.; Weber, G.; Ribavirin and quercetin synergistically downregulate signal transduction and are cytotoxic in human ovarian carcinoma cells. Oncol Res. 1999, 11(5), 243-7.