Thermo Scientific Chemicals

Dimethyl aminoterephthalate, 99%, Thermo Scientific Chemicals

Catalog number: A10567.30
250 g, Each
Thermo Scientific Chemicals

Dimethyl aminoterephthalate, 99%, Thermo Scientific Chemicals

Catalog number: A10567.30
250 g, Each
Quantity
Catalog number: A10567.30
also known as A10567-30
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
5372-81-6
IUPAC Name
1,4-dimethyl 2-aminobenzene-1,4-dicarboxylate
Molecular Formula
C10H11NO4
InChI Key
DSSKDXUDARIMTR-UHFFFAOYSA-N
SMILES
COC(=O)C1=CC=C(C(=O)OC)C(N)=C1
Appearance (Color)
Cream to yellow to green to brown
Form
Powder
Melting Point (clear melt)
129.0-137.0?C
Assay (GC)
≥98.5%

Description

Dimethyl aminoterephthalate is used in the preparation of imidazotetrazinones as probes for the action of temozolomide. It is also used to prepare aminoquinazolines with neurokinin-2 receptor antagonist activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dimethyl aminoterephthalate is used in the preparation of imidazotetrazinones as probes for the action of temozolomide. It is also used to prepare aminoquinazolines with neurokinin-2 receptor antagonist activity.

Solubility
Insoluble in water.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    Precautionary Statements

    P261 - Avoid breathing dust/fume/gas/mist/vapors/spray

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing