Thermo Scientific Chemicals

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%, Thermo Scientific Chemicals

Catalog number: A10807.03
1 g, Each
Thermo Scientific Chemicals

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%, Thermo Scientific Chemicals

Catalog number: A10807.03
1 g, Each
Quantity
Catalog number: A10807.03
also known as A10807-03
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
25952-53-8
IUPAC Name
({[3-(dimethylamino)propyl]imino}methylidene)(ethyl)amine hydrochloride
Molecular Formula
C8H18ClN3
InChI Key
FPQQSJJWHUJYPU-UHFFFAOYSA-N
SMILES
Cl.CCN=C=NCCCN(C)C
Form
Crystals or powder or crystalline powder
Assay from Supplier's CofA
≥98.0%
Appearance (Color)
White
Assay (Titration ex Chloride)
≥98.0 to ≤102.0% (non-U.S. sourced material)
Comment
Material sourced in the U.S. and in other countries

Description

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is used as a carboxyl activating agent. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Solubility
Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.

Notes
Sensitive to moisture. Incompatible with strong acids, strong oxidizing agents and moisture.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Acute oral toxicity
    Category 4
    Acute dermal toxicity
    Category 3
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Skin Sensitization
    Category 1
    Specific target organ toxicity - (repeated exposure)
    Category 2
    Acute aquatic toxicity
    Category 1
    Chronic aquatic toxicity
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H302 - Harmful if swallowed

    H311 - Toxic in contact with skin

    H315 - Causes skin irritation

    H317 - May cause an allergic skin reaction

    H319 - Causes serious eye irritation

    H373 - May cause damage to organs through prolonged or repeated exposure

    H410 - Very toxic to aquatic life with long lasting effects

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P312 - Call a POISON CENTER or doctor if you feel unwell