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2-Mercaptopyridine N-oxide, 99%, Thermo Scientific Chemicals
Catalog number: A14152.06
5 g, Each
Thermo Scientific Chemicals
2-Mercaptopyridine N-oxide, 99%, Thermo Scientific Chemicals
Catalog number: A14152.06
5 g, Each
Quantity
Catalog number: A14152.06
also known as A14152-06
Price (EUR)
59,85 Online price
66,50
Each
Quantity
-
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Chemical Identifiers
CAS
1121-31-9
IUPAC Name
1-hydroxy-1,2-dihydropyridine-2-thione
Molecular Formula
C5H5NOS
InChI Key
YBBJKCMMCRQZMA-UHFFFAOYSA-N
SMILES
ON1C=CC=CC1=S
Specifications
Specification SheetForm
Crystals or powder or crystalline powder
Appearance (Color)
White to cream to yellow to green to grey
Assay (Aqueous acid-base Titration)
≥98.5 to ≤101.5%
Assay (GC)
≥98.5%
Melting Point (clear melt)
67.0-74.0?C
Description
2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.
Solubility
Soluble in tris-hydrochloric acid.
Notes
Incompatible with strong oxidizing agents and strong bases.
2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride.
Solubility
Soluble in tris-hydrochloric acid.
Notes
Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word
Warning
Hazard Statements
H302 - Harmful if swallowed
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
Precautionary Statements
P261 - Avoid breathing dust/fume/gas/mist/vapors/spray
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing