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Triisopropylsilyl trifluoromethanesulfonate, 97%, Thermo Scientific Chemicals
Catalog number: B21127.14
25 g, Each
Thermo Scientific Chemicals
Triisopropylsilyl trifluoromethanesulfonate, 97%, Thermo Scientific Chemicals
Catalog number: B21127.14
25 g, Each
Quantity
Catalog number: B21127.14
Price (EUR)
125,10 Online price
139,00
Each
Quantity
-
Chemical Identifiers
CAS
80522-42-5
IUPAC Name
tris(propan-2-yl)silyl trifluoromethanesulfonate
Molecular Formula
C10H21F3O3SSi
InChI Key
LHJCZOXMCGQVDQ-UHFFFAOYSA-N
SMILES
CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C
Specifications
Specification SheetIdentification (FTIR)
Conforms
Form
Liquid
Refractive Index
1.4120-1.4170 @ 20?C
Appearance (Color)
Clear colorless to yellow
Assay (GC)
≥96.0%
Description
Triisopropylsilyl trifluoromethanesulfonate is used as a reagent for the introduction of triisopropylsilyl(TIPS) group in organic synthesis. It is involved in the synthesis of 2-substituted benzothiopyran-4-ones and silyloxy acetylenes. As a protecting group in organic synthesis, it is utilized especially for the protection of primary amines. Furthermore, it plays an important role in Takahashi Taxol total synthesis or for chemical glycosylation reactions.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Triisopropylsilyl trifluoromethanesulfonate is used as a reagent for the introduction of triisopropylsilyl(TIPS) group in organic synthesis. It is involved in the synthesis of 2-substituted benzothiopyran-4-ones and silyloxy acetylenes. As a protecting group in organic synthesis, it is utilized especially for the protection of primary amines. Furthermore, it plays an important role in Takahashi Taxol total synthesis or for chemical glycosylation reactions.
Solubility
Miscible with chloroform and ethyl acetate.
Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong bases and strong oxidizing agents. Hydrolyzes in water.
Triisopropylsilyl trifluoromethanesulfonate is used as a reagent for the introduction of triisopropylsilyl(TIPS) group in organic synthesis. It is involved in the synthesis of 2-substituted benzothiopyran-4-ones and silyloxy acetylenes. As a protecting group in organic synthesis, it is utilized especially for the protection of primary amines. Furthermore, it plays an important role in Takahashi Taxol total synthesis or for chemical glycosylation reactions.
Solubility
Miscible with chloroform and ethyl acetate.
Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong bases and strong oxidizing agents. Hydrolyzes in water.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 1
Serious Eye Damage/Eye Irritation
Category 1
Label Elements
Signal Word
Danger
Hazard Statements
H314 - Causes severe skin burns and eye damage
Precautionary Statements
P280 - Wear eye protection/ face protection
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician