Thermo Scientific Chemicals

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 97%, Thermo Scientific Chemicals

Catalog number: B25057.22
100 g, Each
Thermo Scientific Chemicals

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 97%, Thermo Scientific Chemicals

Catalog number: B25057.22
100 g, Each
Quantity
Catalog number: B25057.22
also known as B25057-22
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
1892-57-5
IUPAC Name
({[3-(dimethylamino)propyl]imino}methylidene)(ethyl)amine
Molecular Formula
C8H17N3
InChI Key
LMDZBCPBFSXMTL-UHFFFAOYSA-N
SMILES
CCN=C=NCCCN(C)C
Refractive Index
1.4590-1.4630 @ 20°C
Assay (GC)
≥96.0%
Form
Liquid
Appearance (Color)
Clear colorless to yellow
Identification (FTIR)
Conforms

Description

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Solubility
Soluble in water.

Notes
Air sensitive. Incompatible with strong acids and strong oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 1
    Serious Eye Damage/Eye Irritation
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H314 - Causes severe skin burns and eye damage

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P310 - Immediately call a POISON CENTER or doctor/physician