Thermo Scientific Chemicals

3-Chloro-5-fluorophenol, 98%, Thermo Scientific Chemicals

Catalog number: H26195.06
5 g, Each
Thermo Scientific Chemicals

3-Chloro-5-fluorophenol, 98%, Thermo Scientific Chemicals

Catalog number: H26195.06
5 g, Each
Quantity
Catalog number: H26195.06
also known as H26195-06
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
202982-70-5
IUPAC Name
3-chloro-5-fluorophenol
Molecular Formula
C6H4ClFO
InChI Key
ZMFBYTAAMHWQHD-UHFFFAOYSA-N
SMILES
OC1=CC(F)=CC(Cl)=C1
Refractive Index
1.5345-1.5385 @ 20?C
Assay (GC)
≥97.5%
Appearance (Color)
Clear colorless to pale yellow
Form
Liquid

Description

3-Chloro-5-fluorophenol is used as an intermediate in organic synthesis. It plays an important role in the preparation of substituted amides as antagonists and/or inverse agonists of cannabinoid-1 receptor, substituted N-(arylmethyl)aryloxy arylcarboxamide and heteroarylcarboxamide antagonists for the PGE2 receptor EP4 for the treatment of pain, inflammation, osteoarthritis, and rheumatoid arthritis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Chloro-5-fluorophenol is used as an intermediate in organic synthesis. It plays an important role in the preparation of substituted amides as antagonists and/or inverse agonists of cannabinoid-1 receptor, substituted N-(arylmethyl)aryloxy arylcarboxamide and heteroarylcarboxamide antagonists for the PGE2 receptor EP4 for the treatment of pain, inflammation, osteoarthritis, and rheumatoid arthritis.

Solubility
Immiscible with water.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Acute oral toxicity
    Category 4
    Acute dermal toxicity
    Category 4
    Skin Corrosion/Irritation
    Category 1
    Serious Eye Damage/Eye Irritation
    Category 1
    Chronic aquatic toxicity
    Category 2
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H302 + H312 - Harmful if swallowed or in contact with skin

    H314 - Causes severe skin burns and eye damage

    H411 - Toxic to aquatic life with long lasting effects

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting

    P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P310 - Immediately call a POISON CENTER or doctor/physician